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The World Health Organization (WHO) has also become a strong supporter of abstinence. In his official documents, he now uses the turnaround "the less you drink, the better".
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Weight loss medications Ozempic and Wegovy, in particular, have been scrutinized for their high out-of-pocket costs.
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In this fascinating episode of the Huberman Lab Podcast, Andrew Huberman and Dr. Zachary Knight delve into the science behind GLP-1 (Glucagon-Like Peptide-1) and its powerful role in appetite control. They explore the backstory of how this peptide, inspired by a Gila monster’s biology, has revolutionized appetite suppression in humans. With drugs like Ozempic and Monjaro becoming popular for weight management, Dr. Knight explains how GLP-1 functions within the body and brain to reduce hunger and cravings. They also discuss the discovery of this peptide, its effects on animals like the Gila monster, and how researchers have leveraged this knowledge to create treatments that help people manage their appetite and weight. If you're curious about how GLP-1 works and the future of appetite regulation, this episode offers deep insights into the science and potential applications.
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Weight loss has been an industry that is notoriously hard for drug companies to succeed in. Concerns regarding medication use for cosmetic purposes, stigma against people with heavier bodies, and a long history of postmarketing withdrawals of weight-loss medications because of serious side effects make patient education in this field an uphill battle. Today we are going to talk about obesity, the history of drugs to treat it, and the impact of these new drugs - Ozempic, Wegovy and others on patient and physician behavior and how pharma companies are using business strategies to shape this behavior. 60 Minutes Videos: https://youtu.be/DMRnDNhPwqM https://youtu.be/QO5GHr7vZBU Sources and Interesting Reading: Medicare Part D Coverage of Antiobesity Medications — Challenges and Uncertainty Ahead Khrysta Baig, M.S.P.H., Stacie B. Dusetzina, Ph.D., David D. Kim, Ph.D., and Ashley A. Leech, Ph.D. https://www.nejm.org/doi/full/10.1056/NEJMp2300516 Klurfeld, D M, J Foreyt, T J Angelopoulos, and J M Rippe. 2012. "Lack Of Evidence For High Fructose Corn Syrup As The Cause Of The Obesity Epidemic". International Journal Of Obesity 37 (6): 771-773. doi:10.1038/ijo.2012.157. https://www.nature.com/articles/ijo2012157 Elaine Chen, Allison DeAngelis. 2023. "Beyond Wegovy And Ozempic: Biotechs Vie For Piece Of Red-Hot Weight Loss Market With Novel Strategies". STAT. https://www.statnews.com/2023/05/01/weight-loss-obesity-wegovy-ozempic-biotechs-novel-mechanisms/. Silverman, Ed. 2023. "Doctors' Group Complains That 60 Minutes Segment On Wegovy Was Really Just An Ad". STAT. https://www.statnews.com/pharmalot/2023/01/24/wegovy-obesity-60-minutes-fda-weight-loss-advertising/. medicine, nature. 2012. "A History Of Drugs On The Weight List - Nature Medicine". Nature. https://www.nature.com/articles/nm0612-843. Diep, Francie. 2014. "The Science And History Of A Pesticide-Turned-Diet Pill". Popular Science. https://www.popsci.com/article/science/science-and-history-pesticide-turned-diet-pill/. Rodgers, R. John, Matthias H. Tschöp, and John P. H. Wilding. 2012. "Anti-Obesity Drugs: Past, Present And Future". Disease Models &Amp; Mechanisms 5 (5): 621-626. doi:10.1242/dmm.009621. https://www.weightwatchers.com/ Support the channel by using the links below on my favorite services: 💰 - All millennials need a Roth IRA, I use Wealthfront for mine - use my link for $5000 managed free: https://www.wealthfront.com/c/affiliates/invited/AFFA-76TY-2Z07-97XT 💳 - I like the AMEX Platinum because their rewards can't be beat: https://americanexpress.com/en-us/referral/CHIRALCSy9?xl=cp19&mpt=v0 #ozempic #wegovy #mounjaro Disclaimer: These Youtube videos are for entertainment/educational purposes ONLY. If you need advice, please contact the appropriate professional for the subject you would like help with.
