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In continuation of my update "Metformin" GLP-1 receptor agonists, a class of drug used to treat type 2 diabetes, likely trump the widely prescribed metformin for curbing dementia risk in people with the condition, finds the largest study of its kind, published in the open access journal BMJ Open Diabetes Research & Care. The findings suggest that future clinical guidelines for the treatment of type 2 diabetes would do well to consider prioritizing drugs with both blood glucose and neuroprotective effects, say the researchers. Published research suggests that both GLP-1 receptor agonists and metformin, which are widely used to treat type 2 diabetes, protect the brains of people with the disease. But as yet there have been no direct real-world comparisons of the potential impact of these drugs on dementia risk—a risk that is around 70% higher in people with type 2 diabetes. To explore this further, the researchers drew on anonymized electronic health records from a global health research network (Trinetx) spanning the period 2004 to 2024 to track the development of dementia in patients with type 2 diabetes, treated with either GLP-1 receptor agonists or metformin (87,229 patients in each group; average age 58) for at least six consecutive months. There was no significant difference in vascular dementia risk between the two types of drug when used as first line therapy. But GLP-1 receptor agonist use was associated with a significantly lower cumulative (10%) risk of developing dementia, overall, with an incidence of almost 2.5% (2,130 people) compared with an incidence of nearly 5% (4,215 people) for metformin. And specifically, taking this type of drug was associated with a 12% lower risk of developing Alzheimer's disease, and a 25% lower risk of developing non-vascular dementias than metformin use. Further in-depth analyses showed that these positive effects were evident across all age groups, but with the strongest effect among the over 60s, women, and those of white ethnicity. Risk of death from any cause was also lower: nearly 5% of those treated with GLP-1 receptor agonists died compared with nearly 9% of those treated with metformin. "Both medications demonstrate neuroprotective properties, such as reducing neuroinflammation and oxidative stress, improving insulin sensitivity, and enhancing cerebrovascular health, which likely contribute to their benefits in overall dementia," explain the researchers. But unlike metformin, whose benefits primarily derive from systemic metabolic effects, GLP-1 receptor agonists exert direct central nervous system effects by crossing the blood-brain barrier, they add. "However, the multifactorial nature of [vascular dementia], driven by cerebrovascular damage, such as small vessel disease and white matter lesions, poses significant challenges for pharmacological interventions targeting metabolic or neurodegenerative pathways," they continue. This is an observational study, and as such, no firm conclusions can be drawn about cause and effect. And the researchers point out that the tracking period, while sufficient for observing dementia outcomes, may not fully capture long-term cognitive effects, especially given the progressive nature of Alzheimer's disease. REF:https://www.med-chemist.com/2025/07/glp-1-diabetes-drugs-likely-trump.html
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Sure Slim Keto Gummies have taken the weight loss world by storm, promising a slimmer future for those struggling to shed pounds. Featured on Shark Tank, these gummies have garnered attention for their innovative formula and impressive results. If you’re tired of fad diets and strenuous workouts that don’t seem to be working, these gummies may be the answer you’ve been looking for. But do they live up to the hype? Let’s take a closer look at Sure Slim Keto Gummies and what they have to offer.
The Science Behind Sure Slim Keto Gummies
Sure Slim Keto Gummies are designed to help you achieve ketosis, a metabolic state where your body burns fat for energy instead of carbohydrates. This process is known to be an effective way to lose weight, as it helps your body break down stored fat and prevents the accumulation of new fat. The key ingredient in these gummies is BHB (beta-hydroxybutyrate), a type of exogenous ketone that helps kickstart ketosis and accelerate fat burning. By incorporating BHB into your daily routine, you can potentially see faster and more consistent weight loss results.
Additionally, Sure Slim Keto Gummies are packed with essential vitamins and nutrients to support overall health and well-being. This ensures that you’re not only losing weight but also maintaining a balanced and healthy lifestyle. The combination of BHB and these beneficial ingredients makes these gummies a comprehensive solution for weight loss.
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How to Incorporate Sure Slim Keto Gummies Into Your Routine
One of the greatest advantages of Sure Slim Keto Gummies is how easy they are to incorporate into your daily routine. Simply take the recommended dosage of gummies each day, ideally before meals or as directed on the packaging. These gummies are convenient and portable, making them perfect for on-the-go lifestyles. Plus, they come in delicious flavors that make them a treat to enjoy.
In addition to taking Sure Slim Keto Gummies, it’s important to maintain a healthy diet and regular exercise routine for optimal results. While these gummies can help boost your weight loss efforts, they are most effective when combined with a holistic approach to health and wellness. By making small changes to your lifestyle, you can maximize the benefits of these gummies and achieve your weight loss goals more efficiently.
The Benefits of Sure Slim Keto Gummies
There are numerous benefits to incorporating Sure Slim Keto Gummies into your weight loss journey. Some of the most notable advantages include increased energy levels, improved metabolism, and enhanced focus and clarity. Many users report feeling more energized and alert throughout the day, thanks to the ketones in these gummies that provide a steady source of fuel for the body and brain.
Furthermore, Sure Slim Keto Gummies can help suppress appetite and reduce cravings, making it easier to stick to a healthy eating plan. This can lead to fewer instances of overeating or snacking, which are common obstacles in weight loss. By curbing your appetite and promoting satiety, these gummies support better portion control and overall dietary compliance.
Are Sure Slim Keto Gummies Right for You?
Before incorporating any new supplement into your routine, it’s important to consider your individual needs and goals. Sure Slim Keto Gummies may be a great option for those looking to jumpstart their weight loss journey and see tangible results in a shorter amount of time. However, it’s essential to consult with a healthcare provider before starting any new supplement, especially if you have underlying health conditions or are taking medication.
Overall, Sure Slim Keto Gummies offer a convenient and effective way to support weight loss and promote overall well-being. With their innovative formula and powerful ingredients, these gummies have the potential to help you achieve your desired results and feel confident in your body. If you’re ready to take the next step towards a slimmer future, consider giving Sure Slim Keto Gummies a try and see the difference for yourself.
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If you’re working out every day and still stuck — your fat loss plan is broken." More workouts don’t equal more results. In fact, if you’re always tired, wired, and craving sugar — your body’s stressed, not burning fat. Overtraining raises cortisol, wrecks your recovery, and slows fat loss. Here’s what actually works: ✅ 4–5 smart training sessions a week ✅ Enough protein ✅ Prioritizing sleep and nervous system recovery You don’t need to push harder — you need to train smarter. Let go of the guilt when you rest. Let go of the lie that doing more makes you better. Burn fat without burning out. Follow for more real talk on training, mindset, and getting results without losing yourself in the process.
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Have you been struggling to achieve your weight loss goals? Do you find it difficult to stick to a healthy diet and exercise routine? If so, you’re not alone. Many people struggle to lose weight and improve their overall health. Fortunately, there are products on the market that can help you reach your goals more effectively. One such product is Shark Tank BHB Keto Pills.
What are Shark Tank BHB Keto Pills?
Shark Tank BHB Keto Pills are a dietary supplement that claims to help your body enter ketosis more quickly and easily. Ketosis is a metabolic state in which your body burns fat for energy instead of carbohydrates. By entering ketosis, you may experience increased fat burning, improved energy levels, and enhanced mental focus.
These keto pills contain exogenous ketones, which are ketones that are not produced by the body but instead taken as a supplement. Exogenous ketones can help jumpstart the ketosis process and provide additional energy to support your weight loss journey.
Shark Tank BHB Keto Pills also claim to help suppress appetite and reduce cravings, making it easier for you to stick to your diet plan. Additionally, they may help improve digestion and promote overall gut health.
Benefits of Shark Tank BHB Keto Pills
1. Rapid weight loss: Many users report significant weight loss results within a few weeks of taking Shark Tank BHB Keto Pills. By helping your body burn fat more efficiently, these pills can accelerate your weight loss journey.
2. Increased energy levels: The exogenous ketones in these pills can provide a clean, sustained energy source for your body, helping you feel more energized throughout the day.
3. Enhanced mental clarity: Ketones are known to have cognitive benefits, including improved focus and mental clarity. Taking Shark Tank BHB Keto Pills may help you stay sharp and focused throughout the day.
Are Shark Tank BHB Keto Pills Safe?
Before incorporating any new supplement into your routine, it’s important to consult with a healthcare professional. While Shark Tank BHB Keto Pills are generally considered safe for most people, there may be certain individuals who should avoid them, such as pregnant or nursing women, individuals with certain medical conditions, or those taking specific medications.
It’s always best to err on the side of caution and seek professional guidance before starting any new supplement regimen. Additionally, make sure to follow the recommended dosage instructions provided by the manufacturer to ensure optimal results and safety.
Overall, Shark Tank BHB Keto Pills can be a helpful tool in your weight loss journey, but they should be used in conjunction with a healthy diet and exercise plan for best results.
Customer Reviews of Shark Tank BHB Keto Pills
1. “I’ve tried countless diets and supplements in the past, but nothing has worked as effectively as Shark Tank BHB Keto Pills. I’ve lost over 20 pounds in just a few weeks, and I feel more energetic than ever!” – Sarah
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3. “I struggle with cravings and emotional eating, but these keto pills have helped me stay on track and resist temptation. I’ve never felt more in control of my eating habits. Highly recommend!” – Emily
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Frequently Asked Questions
Q: How long does it take to see results with Shark Tank BHB Keto Pills?
A: Results may vary depending on individual factors such as diet, exercise, metabolism, and consistency in taking the pills. Some users report seeing results within a few weeks, while others may take longer to experience significant changes.
Q: Are there any side effects associated with Shark Tank BHB Keto Pills?
A: While Shark Tank BHB Keto Pills are generally safe for most people, some individuals may experience mild side effects such as digestive issues or headaches. It’s important to follow the recommended dosage and consult with a healthcare professional if you have any concerns.
Q: Can I take Shark Tank BHB Keto Pills if I have a pre-existing medical condition?
A: It’s always best to consult with a healthcare provider before taking any new supplement, especially if you have a pre-existing medical condition or are taking medications. Your doctor can help determine if Shark Tank BHB Keto Pills are safe for you to use.
Q: Do I need to follow a strict keto diet while taking Shark Tank BHB Keto Pills?
A: While following a keto diet may enhance the benefits of Shark Tank BHB Keto Pills, it is not necessary to see results. These pills can help your body enter ketosis more easily, even if you don’t strictly adhere to a keto diet. However, maintaining a balanced and healthy diet will optimize your weight loss results.
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