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Tags: Cannabis Research, Adverse Effects, CBD, Cannabis Adverse Events, CBD Side Effects, Medicine Kevin Spelman, PhD, MCPP, presents "Post-Marketing Surveillance of Full-Spectrum Hemp Extract CBD Products for Reported Adverse Events and Serious Adverse Events" at CannMed 23. 0:00 Intro 0:31 Disclosures 1:20 The Problem 2:08 The Solution 2:18 Methods Used 4:05 Phase I - Intake and Documentation of Original Incidents 5:06 Phase II - In Depth Review and Follow-up of Phase I Incidents 6:02 Phase III - Assessment of Strength of Association 7:23 Grades of Adverse Events 7:45 Dose Range 8:20 Results10:09 Summary of Adverse Events 11:30 Results continued 19:45 Previously Documented Adverse Events 20:21 Comparison of Adverse Events There is a paucity of data on the safety of hemp extracts in real-world use. While the number of clinical trials is building, the subject numbers are limited and conditions frequently do not mimic consumer use. Using a retrospective analysis of post-marketing surveillance data on full- spectrum hemp extract products (FSHE-Charlotte’s Web TM ) the frequency of adverse events (AEs) and serious adverse events (SAEs) of these products was assessed by analyzing AE reports and evaluating the total number of AEs against the total number of product units sold. From a total of approximately 1,939,172 product units sold during the 18-month period, 431 AEs were reported from 304 unique individuals, followed by a physician assessment. The incidence of AEs was 0.022% per unit sold. Seven AEs were classified as serious. The most common type of AEs reported were Grade 1 (CTCAE v5.0), and defined as asymptomatic or mild symptoms in the area of gastrointestinal (e.g. general abdominal discomfort) and nervous system disorders (e.g. dizziness/headache). Based on this dataset of spontaneous consumer reporting the FSHE products were determined to result in consumer reports of AEs (0.022%) and SAEs (0.00036%) and to be well tolerated at the recommended doses. These data, with the limitations of self- reports, are intended to be a starting point and we encourage more companies to explore post- marketing surveillance until more robust data are available. Learn More about CannMed: https://cannmedevents.com/
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Existen varios cannabinoides derivados de la planta Cannabis Sativa, pero los dos más abundantes y conocidos son el CBD y el THC; el CBD es conocido por sus propiedades medicinales, mientras que el THC se distingue por sus efectos psicoactivos. El CBD es el cannabinoide predominante en el cáñamo y este contiene niveles muy bajos de THC; tan bajos, que no producen efectos psicoactivos, incluso en el mercado se encuentran algunos nutraceúticos que no contienen THC. RECOMENDACIONES: 1- Antes de automedicarte con cannabis consulta con un médico de confianza o tu médico personal. Si éste carece de conocimientos sobre el uso medicinal de los cannabinoides busca recomendación de uno que tenga el conocimiento. 2- Antes de consumir CBD sin recomendación profesional, es imprescindible consultar con tu médico si estás embarazada o tengas intención de estarlo y/o en el caso de que padezcas algún trastorno psiquiátrico, así como si estás utilizando cannabis y experimentas algún tipo de efecto secundario anormal. La adolescencia es también un periodo de gran vulnerabilidad a los efectos neurológicos no deseados causados por el cannabis. 3- Las instituciones médicas de muchos países están para preparadas para asesorarte en tu correcto tratamiento con cannabinoides, con información relativa a las vías de administración, dosis, composiciones, etc. 4- El producto de cannabis medicinal que vayas a utilizar debe poseer análisis y/o certificaciones fiables sobre su calidad y composición, igualmente sobre la ausencia de productos tóxicos, adicionalmente debe tener en regla los permisos de utilización y comercialización emitidos por las entidades reguladoras de medicamentos y alimentos de tu país. 5- El CBD es un nutraceútico muy seguro (no es citotóxico, ni mutagénico, ni es letal por sobredosis…), pero obviamente no es inocuo y puede tener efectos secundarios, infórmate bien acerca de ellos antes de su uso, y consulta además si pueden existir contraindicaciones o interacciones con tu medicación habitual. 6- Si consumes CBD sin THC no es posible que des positivo en los análisis de tráfico, pero, si consumes THC si es posible que des positivo dependiendo de las dosis. Solicita un certificado de tu uso del cannabis como sustancia medicinal. ¡Síguenos ahora y activa las notificaciones haciendo click en la campana! Entérate de nuestra información más reciente sobre Salud y Bienestar: http://tusaludguia.com FACEBOOK: https://www.facebook.com/tusaludguia/ INSTAGRAM: https://www.instagram.com/tusaludguia... TWITTER: https://twitter.com/TuSaludGuia Producido por @IMAKIFILMS Todos los derechos reservados © Imakinetica SAS - Tu Salud Guía ® 2022 #TuSaludGuia #DanielZapata #cannabismedicinal #CeleneLondoño
