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Welcome to High at Nine News. With your hosts, Jason Beck & Rico Lamitte, joined by industry correspondents and daily antics from around the country. Watch Today's LIVE Episode with this Link: We talk about important topics, shining light on global issues and discussing cannabis as it relates to: Politics, Regulation & Reform. Data & Technology. Science Research & Medicine. Family & Parenting. Art, Celebs & Entertainment. Fitness, Sports, Mental Health & Wellness, Plant Based Medicines & Entheogens. Together we are building a stronger community, fighting the stigma & creating change. Coming to you live Monday through Friday at 9 AM Pacific time and High Noon on the East Coast. Thank you for getting High at 9 with us! PLEASE SUPPORT THE GREEN PARTY: Jillstein2024.com LEARN ABOUT THEIR CANNABIS POLICY WITH THE LINK BELOW: https://ballotpedia.org/Jill_Stein_presidential_campaign,_2016/Marijuana Like what we do? We accept tips via: https://streamelements.com/highat9news/tip Rico Lamitte Jason Beck Dr. Jean Talleyrand Dr. Mark Scialdone Jenny Beth Dills Today is S.T.E.M./S.T.E.A.M. Day, National Parents As Teachers Day, National Harvey Wallbanger Day and National Cappuccino Day. How to capitalize on the Green Wednesday cannabis sales rush https://www.highat9news.com/post/how-to-capitalize-on-the-green-wednesday-cannabis-sales-rush Over half of Miami-Dade voters opposed recreational marijuana. What happened? https://www.highat9news.com/post/over-half-of-miami-dade-voters-opposed-recreational-marijuana-what-happened CBD Oil Mitigates Neuropsychiatric Symptoms in Alzheimer’s Patients https://www.highat9news.com/post/study-cbd-oil-mitigates-neuropsychiatric-symptoms-in-alzheimer-s-patients Cannabis-Based Phytocannabinoids: Overview, Mechanism of Action, Therapeutic Application, Production, and Affecting Environmental Factors https://www.highat9news.com/post/cannabis-based-phytocannabinoids-overview-mechanism-of-action-therapeutic-application-production Illinois government blamed for failing social equity cannabis businesses in new lawsuit https://www.highat9news.com/post/illinois-government-blamed-for-failing-social-equity-cannabis-businesses-in-new-lawsuit Massachusetts voters reject proposal to legalize certain psychedelic drugs https://www.highat9news.com/post/massachusetts-voters-reject-proposal-to-legalize-certain-psychedelic-drugs _________________________________________________________________________________________ SUBSCRIBE TO THE MAIN CHANNEL : youtube.com/@highat9news SUBSCRIBE TO THE NEWS CHANNEL : youtube.com/@highatninenews LIKE, COMMENT, SHARE CHECK OUR WEBSITE for MORE! : www.highat9news.com MERCH: https://highat9news-shop.fourthwall.com/? ________________________________________________________________________________________ SUPPORT OUR SPONSORS CATALYST RETAIL STORES https://catalyst-cannabis.com PATRIOT BUSINESS FINANCE https://patriotbfc.com/ Parody Gummy https://www.parodygummy.com/ Family's Best Jerky https://www.familysbestjerky.com/ ________________________________________________________________________________________ INSTAGRAM: https://www.instagram.com/highat9newshour/ TWITTER/ X: https://twitter.com/highat9news FACEBOOK: https://www.facebook.com/highat9news TWITCH: https://www.twitch.tv/highat9news LINKEDIN: https://www.linkedin.com/company/high-at-9-news/ RUMBLE: https://rumble.com/c/c-2255934 —----------------------------------------------------------------------------------------------------------- FOLLOW YOUR HOSTS: JASON: IG: https://www.instagram.com/jasonbeck420/ TWITTER / X: https://twitter.com/JasonBeck420 LINKEDIN: https://www.linkedin.com/in/jasonbeck420/ RICO: IG: https://www.instagram.com/ricolamitte/ TWITTER / X: https://twitter.com/RicoLamitte LINKEDIN: https://www.linkedin.com/in/rico-lamitte-a64bb616/
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THC is the main psychoactive component of cannabis. In this video, I discuss the effects of THC on the nervous system. TRANSCRIPT: THC is the main psychoactive component of cannabis, and one of a class of compounds known as cannabinoids. Cannabis tends to be relatively low in THC compared to its levels of a THC precursor, THCA. Heating the cannabis plant, however, causes the conversion of THCA to THC, which is part of the basis for heating or burning the plant for use. The effects of cannabis may vary depending on the variety of cannabis plant and its associated levels of THC and other cannabinoids, but common effects of THC include: euphoria, sedation, stimulation of appetite, impaired cognitive function, analgesia, and anxiety. THC is thought to exert most of its effects by binding to receptors called cannabinoid receptors. There are two known cannabinoid receptors, CB1 and CB2--both of which are g-protein coupled receptors. CB1 receptors are found throughout the nervous system, while CB2 receptors are primarily found on immune cells. THC acts as a partial agonist at cannabinoid receptors, meaning it binds to these receptors and generates a response that’s a fraction of what other substances that bind to the receptors can generate. THC interacts with a number of other targets as well, but it’s thought that its main psychoactive effects are mediated through its action at CB1 receptors. Activation of CB1 receptors is thought to lead to the modulation of the release of various neurotransmitters. It’s not fully understood how this translates into the characteristic effects of THC, but the activation of CB1 receptors in different areas of the nervous system may partially explain the effects of the drug. CB1 receptors in areas like the cortex and hippocampus, for example, may be involved in the perceptual and cognitive effects of THC, CB1 receptors in areas like the basal ganglia and cerebellum may be associated with sedation and effects on movement, and CB1 receptors in areas like the spinal cord and brainstem may be linked to analgesic effects. REFERENCES: Banister SD, Arnold JC, Connor M, Glass M, McGregor IS. Dark Classics in Chemical Neuroscience: Δ9-Tetrahydrocannabinol. ACS Chem Neurosci. 2019;10(5):2160‐2175. doi:10.1021/acschemneuro.8b00651 Howlett AC, Barth F, Bonner TI, et al. International Union of Pharmacology. XXVII. Classification of cannabinoid receptors. Pharmacol Rev. 2002;54(2):161‐202. doi:10.1124/pr.54.2.161 Pertwee RG. Pharmacological actions of cannabinoids. Handb Exp Pharmacol. 2005;(168):1‐51. doi:10.1007/3-540-26573-2_1 Pertwee RG. The diverse CB1 and CB2 receptor pharmacology of three plant cannabinoids: delta9-tetrahydrocannabinol, cannabidiol and delta9-tetrahydrocannabivarin. Br J Pharmacol. 2008;153(2):199‐215. doi:10.1038/sj.bjp.0707442
