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W odcinku „ODC 89 Neurotoksyczność THC i CBD – co mówi nauka?” zapraszam na rozmowę z dr. Konradem Kowalskim – dyrektorem ds. naukowych w firmie Mazdiak, ekspertem w dziedzinie biochemii, biotechnologii, diagnostyki medycznej i spektrometrii masowej. Omawiamy najnowsze badania nad metabolizmem i akumulacją kannabinoidów w mózgu, poruszamy temat neurotoksyczności THC i CBD, wyjaśniamy, dlaczego nawet preparaty z konopi włóknistych mogą prowadzić do efektów behawioralnych i jak forma podania oraz pora dnia wpływają na biodostępność. Jak długo THC i CBD zostają w mózgu? Czy fitokannabinoidy mogą być neurotoksyczne? Czy legalne ekstrakty mogą wywołać niespodziewany „haj”? Dowiesz się także, jak zoptymalizować terapię konopną, aby była skuteczna i bezpieczna – zarówno dla dzieci, jak i dorosłych. Ten odcinek to solidna dawka wiedzy dla pacjentów, terapeutów, lekarzy oraz wszystkich zainteresowanych medycyną konopną i zdrowiem mózgu. 🎙️ Posłuchaj, subskrybuj i podziel się odcinkiem! 📲 Znajdź nas na: rozmowykonopne.pl, YouTube, Spotify, Instagram i X 📩 Zapisz się do newslettera, aby otrzymać dodatkowe materiały edukacyjne i zapowiedzi nowych odcinków. Z odcinka dowiesz z tego odcinka: Czym jest neurotoksyczność i jak dotyczy naturalnych kannabinoidów. Jak długo THC i CBD utrzymują się w mózgu w zależności od formy podania. Dlaczego pacjenci mogą doświadczać efektów THC, mimo że przyjmują „czyste CBD”. Jak długo THC akumuluje się w mózgu w porównaniu z CBD. Jak dieta i pora dnia wpływają na biodostępność fitokannabinoidów. Jakie są zagrożenia długotrwałego stosowania ekstraktów z THC. Dlaczego testowanie poziomu kannabinoidów we krwi może pomóc w terapii. Tomasz Ołubczyński www.RozmowyKonopne.pl Dr Konrad Kowalski Chief Science Officer (CSO) [email protected]  www.masdiag.pl Pomóż budować wartościowy content - wspieraj kanał na Patronite Spis rozdziałów: 00:00:00 – Wstęp 00:01:30 – Czym jest neurotoksyczność? 00:06:50 – Fitokannabinoidy a mózg – mechanizm działania 00:12:40 – Czy CBD może działać jak THC? 00:19:00 – Metabolizm kannabinoidów – jak długo zostają w mózgu? 00:25:30 – Przykład pacjenta z glejakiem i niespodziewaną reakcją 00:32:45 – Syntetyczne vs naturalne kannabinoidy – zagrożenia 00:39:15 – Znaczenie dawkowania i pora dnia w terapii 00:47:00 – CBD vs THC: czas działania i neurotoksyczność 00:54:30 – Wnioski

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In this video, I test out Lion’s Mane and CBD on my sleep to determine what works best using my Oura Ring data. I’ve been recording my sleep data for over a year now using the Oura Ring so I have a good baseline for my Deep and REM sleep scores. In my two week experiment with Lion’s Mane for half and CBD for the other, I’m going to show you what kind of impact these had on my sleep data. ---------------------------------------------------------- PRODUCT LINKS: Lion's Mane from Wild Kingdom: https://wildkingdomextracts.com/discount/katie&jasper 15% OFF + FREE SHIPPING ON ALL ORDERS using code KATIE&JASPER at Checkout Lion's Mane with Kakadu Plum by Life Cykel: https://amzn.to/38SbWv5 Four Sigmatic Mushroom Powders: https://amzn.to/3d0B8Tn CBD 30:1 by Papa and Barkley: https://papaandbarkley.com/ MedTerra CBD: https://medterracbd.com/ Onda Wellness CBD: https://ondawellness.com/ - SIGN UP FOR OUR SECRET HANDSHAKE! https://katie-moore-youtube.ck.page/82a9a2c553 - LET'S BE FRIENDS:: https://www.instagram.com/katiegracemoore - LOVE THIS STUFF: https://www.katie-moore.com/shop-favorites - THE BLOG: https://www.katie-moore.com/blog Resources: Buy Oura ($299): https://ouraring.com/ Why We Sleep Book: https://amzn.to/2WgmGB1 CBD and Toxicity: https://www.openaccessgovernment.org/take-too-much-cbd/71920/ CBD Oil Review: https://cbdoilreview.org/cbd-cannabidiol/cbd-dosage 7 REASONS YOU SHOULD TAKE CBD OIL FOR SLEEP: https://papaandbarkley.com/cbd-oil-for-sleep/ LION’S MANE BEFORE BED: HOW THIS MUSHROOM SUPPORTS SOUND SLEEP: https://www.mushroom-revival.com/lions-mane-before-bed/ More information: Lion’s Mane has been celebrated as a cognitive booster and here’s why… * Contains brain boosting compounds known as Erinacines. * stimulates nerve growth factor - protein supports the growth and survival of developing and mature neurons * Recommended for improved memory, focus, cognition * There are no human studies done on Lion’s mane’s possible effect on sleep quality, but considering its effects on stimulating BDNF/NGF it could very well also promote better sleeper * No human studies have examined the side effects of lion's mane mushroom or its extract, but they appear to be very safe. No adverse effects have been seen in rats, even at doses as high as 2.3 grams per pound (5 grams per kg) of body weight per day for one month or lower dosages for three months Cannabidiol (CBD), the non-psychoactive compound found in cannabis * CBD acts on receptors throughout the body known as the endocannabinoid system. The endocannabinoid system affects many physiological processes, including the body’s hormone levels, immune system, sleep/wake cycles and pain receptors. * CBD has been used in the treatment of insomnia - A common cause of insomnia is anxiety and stress. CBD helps to regulate cortisol, a stress hormone, which has a significant impact on non-REM sleep cycles. A large case series review found that CBD is beneficial for anxiety-related disorders and an increase in sleep quality. * Research shows CBD may increase overall sleep amounts and reduce insomnia. CBD has also been shown to improve sleep in people who suffer from chronic pain. MY FAVORITE PRODUCTS: Track your sleep with the Oura Ring: https://ouraring.com/ - - - Watch my review: https://youtu.be/D84US6SuERA Fall asleep and stay asleep! Wear these glasses before bed!: https://amzn.to/2WfgKrR - - - Watch my review: https://youtu.be/KokadFH1LzU My Red light therapy panel: https://amzn.to/3a4FOpL The massage gun I wish I owned..: https://amzn.to/2vZYGYc - - - Watch the review of the one I own: https://youtu.be/zEFiRE6PJXI Hack Meditation with the Muse 2: Buy the Muse 2: https://amzn.to/2QkvHFn - - - Watch my review: https://youtu.be/JZo66KrmrKk MY FAVORITE BRAIN BOOSTING SUPPLEMENTS: The king of focus - Qualia Mind (caffeine free): https://amzn.to/2TTJCnK Qualia Mind: https://amzn.to/2waGmeH Alpha Brain Instant: https://amzn.to/33nh8WB Quicksilver Noto Bravi: https://amzn.to/2WeTlH5 Life Cykel Lion's Mane: https://amzn.to/38SbWv5 Four Sigmatic Mushroom Powders: https://amzn.to/3d0B8Tn SUBSCRIBE FOR MORE VIDEOS: I'm Katie and I'm Type A. My mission is to help YOU achieve success without sacrificing your health or happiness! If you are new to the channel, welcome! Excited to have you join the Type A Tribe! Connect with me on social! @KatieTypeA Everywhere! FOLLOW ME: Instagram: https://www.instagram.com/katietypea Medium: https://medium.com/@katietypea Facebook: https://www.facebook.com/katietypea TikTok: https://www.tiktok.com/@katietypea Twitter: https://twitter.com/katietypea Website (and merch!): https://katietypea.com

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Medical marijuana is hitting the mainstream, and with that, there are new opportunities for therapies. Many people with Parkinson's swear by the use of CBD capsules or oils to help with dyskinesia, tremor, and pain. What are your thoughts on this? I was diagnosed with young onset Parkinson's disease at the age of 33 in 2011, and I had a huge, spiraling fall. I was depressed and was ready to give up. That's when I decided I when I decided I needed to focus more on my health. I learned everything I could about the disease and reshaped my life. Today I'm stronger, physically an emotionally, than I was when I was first diagnosed. If I can do it, so can you. Stay strong. Keep fighting. Don't ever give up! Buy my book: https://amzn.to/31HEuoE FB: https://www.facebook.com/parkinsonswarrior TW: https://twitter.com/parkinsonswar ❱❱❱❱ WELCOME ❰❰❰❰ HELLO! If you're new to my channel, please subscribe! I'll show you how to improve your life by fighting Parkinson's on your terms. // MUSIC // Music by bensound.com

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