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Is Cannabinoid Hyperalgesia Linked To Tolerance? In this informative video, we will discuss the relationship between cannabinoids and pain management. Cannabinoid hyperalgesia is a phenomenon that can occur with long-term use of cannabinoids, leading to increased sensitivity to pain instead of relief. We will explore how tolerance develops with the use of cannabinoids, particularly Δ9-tetrahydrocannabinol, the main psychoactive component of cannabis. You will learn about the neuroadaptive changes that take place in the body, including the downregulation of cannabinoid receptors, which can diminish the effectiveness of pain relief over time. We will also look at clinical observations and studies that indicate chronic cannabis users may experience lower pain tolerance compared to non-users. Additionally, this video will cover potential strategies that researchers are investigating to mitigate the risks associated with cannabinoid use for chronic pain, including alternative agonists that may have less impact on receptor desensitization. Understanding the complexities of cannabinoid use in pain management is essential for anyone considering these treatments. Join us for this engaging discussion, and subscribe to our channel for more helpful information on pain medicine and management. ⬇️ Subscribe to our channel for more valuable insights. 🔗Subscribe: https://www.youtube.com/@PainMedicineNetwork/?sub_confirmation=1 #CannabinoidHyperalgesia #PainManagement #ChronicPain #CannabisUse #Tolerance #PainRelief #Cannabinoids #Healthcare #PainMedicine #ChronicPainManagement #Research #MedicalCannabis #PainSensitivity #ClinicalObservations #CannabisResearch #PainTherapy About Us: Welcome to Pain Medicine Network, your trusted source for comprehensive information on pain management and treatment options. Our channel is dedicated to exploring the latest advancements in pain medicine, offering insights into innovative therapies, research breakthroughs, and expert interviews. Please note that our content is purely informational and should not be considered medical advice. Always consult a healthcare professional for personalized guidance and do your own due diligence when it comes to your health and treatment options. The content provided is for general informational and educational purposes only. It is not intended to substitute for professional medical advice, diagnosis, or treatment. Never disregard professional medical advice or delay seeking it because of something you have seen in this content. Never rely on this information in place of consulting with qualified healthcare professionals. The creators and distributors of this content are not responsible for any adverse effects or consequences resulting from the use of any suggestions, preparations, or procedures described in this material. Always consult with your healthcare provider before starting any new health-related practice or program.

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Evan Birch (Guy Pearce) is a family man and esteemed professor at a distinguished college, where his charm and reputation have made his philosophy class very popular. When a female student named Joyce goes missing, Evan’s previous off-campus dalliances make his wife (Minnie Driver) question his alibi. Gruff police Detective Malloy (Pierce Brosnan) has even more reason to be suspicious when crucial evidence makes Evan the prime suspect in Joyce’s disappearance. Suddenly, the questions Evan faces aren’t merely academic – they’re a matter of life or death. SPINNING MAN is in theaters and on demand April 6th, 2018.

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Midas Letter RAW highlights the stocks and stories to watch in the Canadian markets today. James West and Ed Milewski provide comprehensive fundamental & technical analysis on all trending business and investment news, while interviewing the top CEOs of all public companies and analysts with the highest reputations in the business. 0:00 - Macroeconomics and Cannabis Analysis with James & Ed -epic S&P action -significant volatility 4:16 - Midas letter News -Fincanna Capital Corp (CNSX:CALI) debenture announcement -TILT Holdings Inc (CNSX:TILT) announce appoint of new CFO -Yield Growth Corp (CNSX:BOSS) applies for research and medical licenses -Curaleaf (CNSX:CURA) opens 36th dispensary -Auxly (CVE:XLY) appoints new leadership team members -Next Green Wave (CNSX:NGW) deal for seed to sale in California -Sunniva (CNSX:SNN) marks first cannabis products sales in California 7:38 - Macroeconomics and Cannabis Analysis with James & Ed -markets acting independent of macro news 8:45 - Charlotte’s Web Holdings Inc (CNSX:CWEB) (OTCMKTS:CWBHF) is the category leader in hemp extracted health and wellness products in the United States. CEO Hess Moallem provides an overview of the company’s operations and 2019 goals. 17:16 - Macroeconomics and Cannabis Analysis with James & Ed -Charlotte's Web is the original CBD product available in the US; epilepsy treatment -CWEB chart: lots of volatility; but superb resilience -first mover advantage -Wayland Group (CNSX:WAYL) bought 50% of similar company in UK (epilepsy treatment driving legalization) -International Cannabrands (JUJU) up about 6% -Patriot One (PAT) has was halted, resumed trading today; big jumps today -Organigram Holdings (TSE:OGI) holding at $5.70; if you bought it at $4 something, maybe it's time to cash in -Q: is ACB going to break to the upside or downside? A: to the upside -Aphria coming out with earnings next week; Aphria chart suggesting a base; good news can give it a bump 30:37 - Trivia Question: What subject did Jerry Garcia use his concert goers to explore? 31:29 - Analyst Dmitry Zaytsev breaks down the holiday season’s shifting market trends. He notes that the bottoming trend he anticipated in December has been realized and that the current excitement in the cannabis space is focused on mid-cap names. 44:14 - Trivia Answer: a) telepathy and ESP 45:20 - Macroeconomics and Cannabis Analysis with James & Ed Q: What does Tilray need to do to justify valuation? A: Show me the money; just report profits quarter after quarter -Patriot One Technologies: halted this morning automatically (too much volume); don't like the last candle with the big wick; halted for only 7 minutes (no official news) -Tilray (NASDAQ:TLRY) chart: Ed: don't like this chart; valuation concerns, at the low end of its retreat; more stock coming in two weeks -Tinley chart (TNY): bit of a run last few days -what does the chart action tell you about the Green Growth Brands (GGB) takeover of Aphria potential? GGB thinly traded but going up (potential buy?) 57:17 - Video - Cannabis and Skincare: Adamo Barbieri takes a look emerging cannabis skincare products and companies like Khiron Life Sciences that are leaders in the space. 1:00:40 - Macroeconomics and Cannabis Analysis with James & Ed -Khiron CBD skincare products -Q: What do you think of Village Farms (VFF)? A: part of huge greenhouse conglomerate, not doing enough marketing -store.midasletter.com -products will be available through Midas Letter site; shop launching soon -Canopy Growth (TSE:WEED) chart: -only the mid-caps are rallying right now -Q: how interested are consumers in organic cannabis? A: I only buy organic but probably 15-20% of market -S&P had epic collapse in December; but nice move today, took out previous highs; working toward break down level? -Q: What's going on with Heritage Cannabis (CNSX:CANN)? A: look at chart; Ed doesn't like the look of the chart -ML large cap index up 1%; S&P up 3% 1:29:14 - Bloopers ************************ Check out our website: https://midasletter.com ************************ SUBSCRIBE to our YouTube: http://bit.ly/MidasLetterYoutube SUBSCRIBE to our 2nd YouTube Channel - Midas Letter Clips: https://bit.ly/2rtQzgy SUBSCRIBE to our Newsletter: http://bit.ly/MidasLetterNewsletter Download Our Podcast on iTunes: http://bit.ly/MidasLetterPodcast ************************ Follow Us on Twitter: http://bit.ly/MidasLetterTwitter Like Us on Instagram: http://bit.ly/MidasLetterInsta Like Us on Facebook: http://bit.ly/MidasLetterFacebook ************************ #WeedStocks #TechnicalAnalysis #MidasLetter

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Curious about cannabis? In Part 1 of our Frequently Asked Questions About Cannabis series, we dive into the most common questions surrounding cannabis use, legality, effects, and more. Whether you're a beginner exploring cannabis for the first time or a seasoned user looking to stay informed, this video has something for you. We'll cover: 1. What's the difference between Hemp & Marijuana? 2. What is classified as Hemp? 3. What is CBD, and how is it different from THC? 4. What are the benefits of CBD? 5. Are hemp or CBD products safe to consume? 6. Will I fail a drug test if I'm using CBD? Stay tuned for Part 2, where we’ll continue breaking down your most-asked questions! 👉 Don't forget to like, comment, and subscribe for more cannabis education, tips, and product breakdowns from the experts at RESTART! 📲 Visit https://www.restartcbd.com for premium hemp products and more helpful resources. #CannabisFAQ #CannabisEducation #CBD #THC #RestartCBD #HempWellness #TexasHemp #texascannabis #texaslegislation

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We are here to discuss the potential benefits, uses, and side effects of CBD oil. CBD oil is derived from the cannabis plant, but it does not contain the psychoactive compound THC, so it does not produce a "high" effect. Some studies suggest that CBD oil may have potential therapeutic benefits for conditions such as anxiety, chronic pain, and epilepsy. CBD oil may also have some side effects, including drowsiness, dry mouth, and changes in appetite and mood. CBD is available in various forms such as oil tinctures, capsules, and edibles. The best form and dosage depend on the individual's needs and preferences. It is important to understand that everyone absorbs CBD differently, depending on age, weight, and lifestyle. There is no standard dosing requirement to follow but you should always start low and slow with your dosing. If you are new to CBD and take other types of medication, be sure to consult a healthcare provider before using CBD oil. Always do your research before choosing the right CBD products. It is important to choose products from reputable sources and that means to check for third-party lab testing to ensure quality and purity. CBD2GO.co

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