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On this episode of the podcast, we tackle something that is growing rapidly in popularity—CBD—but does it live up to its hype? After the Farm Bill in 2018, it was legal to grow hemp, from which CBD (cannabidiol) can be derived. As a result, many supplement companies emerged selling a wide array of CBD-containing products: from oral drops, to lotions/salves, to shampoos, to even food products. While there are some limited data to suggest that CBD can be beneficial with regard to certain medical issues such as anxiety, insomnia, and others – more data are needed. Unfortunately, the enthusiasm behind CBD has outpaced the science demonstrating therapeutic benefits. More concerning – CBD is an inhibitor of a critical enzyme in our body: Cytochrome P450 CYP3A4. This enzyme is responsible for metabolizing the majority of prescribed medications including certain antibiotics, acetaminophen, codeine, steroids, diazepam, and carcinogens. As such, inhibiting this enzyme may lead to accumulation of medications that can have potentially serious consequences and drug interactions. All CBD sold currently are supplements, aside from one CBD-containing product that is FDA approved for a very explicit use in rare forms of epilepsy. As such, these products are not regulated for purity, concentration, efficacy, or safety. More than that, it is illegal for these companies to make therapeutic claims. That’s true for our pets, too. To date, there have been only a few very small studies in dogs, and in cats, only a single small trial have investigated the SAFETY of CBD – no data exist to demonstrate efficacy for any medical issue. The TL;DR: CBD is potentially beneficial for certain medical issues – but is not a panacea for the wide array of ailments many companies advertise. More data and research are needed – and more standardization for CBD-containing products is essential. We cover a lot of ground in this episode—you don’t want to miss it! Find us on all social media platforms! Facebook: https://www.facebook.com/unbiasedscipod Twitter: https://twitter.com/unbiasedscipod LinkedIn: https://www.linkedin.com/showcase/unbiased-science-podcast/posts/ Instagram: https://instagram.com/unbiasedscipod TikTok: https://www.tiktok.com/@unbiasedscipod Spotify: https://open.spotify.com/show/7JMSODgbC5auqScduzYVZn Link to our shop for Unbiased Science merch and our personally recommended items for you: https://unbiasedscipod.carrd.co/
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