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A drug dealer who caused the death of a seven-year-old boy in an explosion while making cannabis gummy sweets has been jailed for 14 years. Reece Galbraith and his friend Jason “Jay” Laws were using a Newcastle flat as a drugs lab when a blast ripped through the building in the early hours of October 16. The explosion killed Laws and Archie York, who was asleep in the flat above. Galbraith, of Rectory Road, Gateshead, Tyne and Wear, admitted two counts of manslaughter as well as possessing and supplying cannabis, at a hearing last month. On Wednesday he was jailed for 14 years at Newcastle Crown Court. Daily Record Homepage: https://www.dailyrecord.co.uk/ Daily Record Facebook: https://facebook.com/TheScottishDailyRecord Daily Record Instagram: https://instagram.com/scottishdailyrecord Daily Record Sport Instagram: https://instagram.com/dailyrecord_sport Daily Record TikTok: https://www.tiktok.com/@scottishdailyrecord Daily Record Sport TikTok: https://www.tiktok.com/@dailyrecord_sport Daily Record Twitter: https://twitter.com/Daily_Record Daily Record Newsletters: https://www.dailyrecord.co.uk/newsletter-preference-centre/ Join our WhatsApp communities here and get the latest news sent straight to your messages: DAILY RECORD: https://www.dailyrecord.co.uk/news/scottish-news/join-daily-records-whatsapp-community-31116469 RECORD SPORT RANGERS: https://www.dailyrecord.co.uk/sport/football/join-record-sports-new-rangers-31111892 RECORD SPORT CELTIC: https://www.dailyrecord.co.uk/sport/football/join-record-sports-new-celtic-31111589 You can get all the latest news, sport, showbiz and comment at DailyRecord.co.uk LIKE | COMMENT | SUBSCRIBE | SHARE #DailyRecord #cannabis #explosion #court
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We’ve already learned a bit about substitution reactions in organic chemistry and the two different paths they can follow: SN1 and SN2. In order to better predict the products of a substitution reaction and understand how they work, we need to be able to figure out which mechanism a reaction is likely to follow. In this episode of Crash Course Organic Chemistry, we’ll deepen our knowledge of substitution reactions by looking at factors like substrate structure and reaction conditions to determine whether SN1 or SN2 is the more likely mechanism. Episode Sources: Brookes, P., Lawley, P.D. “The Reaction of Mono-and Di-Functional Alkylating Agents with Nucleic Acids,” , Biochem. J., 1961, 80, 496-503. Copley, Shelley, D., “Microbial dehalogenases: Enzymes recruited to convert xenobiotic substrates,” Current opinion in Chemical Biology, 1998, 2, 613-617. Janssen, D. B., Scheper, A., Dijkhuizen, L, Witholt, B., “Degradation of halogenated aliphatic compounds by Xanthobacter autotrophicus GJ10,” Applied and Environmental Microbiology, 1985, 29, 673-677. Silberstein, M., Dambrosky, J., Vajda, S., “Exploring the binding sites of the haloalkane dehalogenase Dhla from Xanthobacter autotrophicus GJ10,” Biochemistry, 2007, 46,9239-9249. Brunning, Andy, “The chemistry of dry cleaning,” https://cen.acs.org/articles/95/i45/Periodic-graphics-chemistry-dry-cleaning.html McCoy, M., “Dry Cleaning Dreams,” Chemistry and Engineering News, 2005, 83(46), 19-22. Series Sources: Brown, W. H., Iverson, B. L., Ansyln, E. V., Foote, C., Organic Chemistry; 8th ed.; Cengage Learning, Boston, 2018. Bruice, P. Y., Organic Chemistry, 7th ed.; Pearson Education, Inc., United States, 2014. Clayden, J., Greeves, N., Warren., S., Organic Chemistry, 2nd ed.; Oxford University Press, New York, 2012. Jones Jr., M.; Fleming, S. A., Organic Chemistry, 5th ed.; W. W. Norton & Company, New York, 2014. Klein., D., Organic Chemistry; 1st ed.; John Wiley & Sons, United States, 2012. Louden M., Organic Chemistry; 5th ed.; Roberts and Company Publishers, Colorado, 2009. McMurry, J., Organic Chemistry, 9th ed.; Cengage Learning, Boston, 2016. Smith, J. G., Organic chemistry; 6th ed.; McGraw-Hill Education, New York, 2020. Wade., L. G., Organic Chemistry; 8th ed.; Pearson Education, Inc., United States, 2013. *** Watch our videos and review your learning with the Crash Course App! Download here for Apple Devices: https://apple.co/3d4eyZo Download here for Android Devices: https://bit.ly/2SrDulJ Crash Course is on Patreon! You can support us directly by signing up at http://www.patreon.com/crashcourse Thanks to the following patrons for their generous monthly contributions that help keep Crash Course free for everyone forever: Christine Phelan, Nick, DAVID MORTON HUDSON, Perry Joyce, Scott Harrison, Mark & Susan Billian, Junrong Eric Zhu, Alan Bridgeman, Jennifer Smith, Matt Curls, Tim Kwist, Jonathan Zbikowski, Jennifer Killen, Sarah & Nathan Catchings, Brandon Westmoreland, team dorsey, Trevin Beattie, Eric Koslow, Indika Siriwardena, Khaled El Shalakany, Shawn Arnold, Siobhán, Ken Penttinen, Nathan Taylor, William McGraw, Laura Damon, Andrei Krishkevich, Eric Prestemon, Jirat, Brian Thomas Gossett, Ian Dundore, Jason A Saslow, Justin, Jessica Wode, Mark, Caleb Weeks __ Want to find Crash Course elsewhere on the internet? Facebook - http://www.facebook.com/YouTubeCrashCourse Twitter - http://www.twitter.com/TheCrashCourse Tumblr - http://thecrashcourse.tumblr.com Support Crash Course on Patreon: http://patreon.com/crashcourse CC Kids: http://www.youtube.com/crashcoursekids
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ERCP - Endoscopic Retrograde CholangioPancreatography is the method of choice these days to remove stone from CBD. Stone usually slips from gall bladder but may form in CBD itself in some cases. Ayushman Bharat provides free treatment with ERCP and Laparoscopic Gall Bladder Surgery at STAR Hospital. We at STAR Hospital perform ERCP and can do Laparoscopic Cholecystectomy (Key Hole Surgery to remove Gall Bladder) at the same time or next day - thereby saving your time and enabling quick recovery of patient. We have the facility to do both procedures in the same Modular Operation Theatre which gives our patients quick recovery. This testimonial by one of our many such patients depicts the same. STAR Hospital - Region's First Internationally Certified Super-Specialist Centre for Bariatric Surgery and Advanced Laparoscopic Surgery. Dr. Jasmeet Singh Ahluwalia (MS, FNB-MAS, FBMS) Super-Specialist Bariatric, Metabolic & Advanced Laparoscopic Surgeon Helpline: +91-9888958889 Website: http://drjasmeetahluwalia.com YouTube channel : https://youtube.com/c/drjasmeetsinghahluwalia Facebook page: https://m.facebook.com/drjasmeetahluwalia/ Google Map Link - Dr Jasmeet Singh : http://location.drjasmeetahluwalia.com Star Hospital : http://location.thestarhospital.com Appointment: 0181-4674888 For International Patients- - Tour planning & help in medical visa - Airport pickup and drop - Deluxe Suit - Local accomodation - Long term followup from India Why is ERCP performed? Jaundice (yellowing of eyes or skin). Abnormal liver blood tests. Blockage of bile or pancreatic ducts caused by stone, cancer or narrowing (stricture). To alleviate bile leak after surgery How is it done? A special endoscope is inserted through mouth and opening of CBD (pipe connecting liver with bowel) is entered. Then stone is removed and a stent may be left in place to keep it open for some time. In case of cancers, stent helps to keep CBD open and relieve jaundice. In cases of stricture, a balloon can be used to dilate it. By injection of a dye which can be immediately viewed on Xray, we can get more information about bile ducts and pancreatic ducts. An ERCP can give more information about the pancreas and bile ducts, and brushings and biopsies (specimens of cells for analysis) can be taken from the bile ducts or the pancreas. Risks? ERCP is generally safe but complications can sometimes occur. Mild- Mild abdominal discomfort Sore throat Mild pancreatitis Inability to gain access to the bile or pancreatic ducts Major- Severe pancreatitis can occur following an ERCP but is rare Infection in the bile duct can occur (cholangitis). Usually settles with antibiotics Bleeding - usually stops quickly by itself Very frail and/or elderly patients can get pneumonia A hole may be made in the wall of the duodenum (perforation), either as a result of sphincterotomy or due to a tear made by the endoscope. This happens in less than one in 750 cases and might require surgery Although ERCP carries risks, it is only carried out when the doctors have carefully balanced the risks of doing this test compared with doing any other test or operations, and the risks of doing nothing. Laparoscopic Cholecystectomy- This surgery is performed to remove gall bladder. Gall Bladder is a small pear shaped organ which lies under liver in right upper part of your abdomen as shown in pictures above. Its function is to store bile (digestive juice) secreted by liver in-between meals. Since its size is small as compared to amount of bile produced by liver, it concentrates bile inside it. When bile becomes too concentrated, stones are formed. Common symptoms of Gall Bladder stones – They may not cause any symptoms at all for many years. Pain in the right upper abdomen (Can be in upper centre abdomen as well) when stone blocks gall bladder. Pain may be short lasting if stone dislodges quickly (called biliary colic) or may be long lasting when gall bladder becomes inflamed and may start to have infection inside it. Nausea or vomiting may occur as well. Loss of appetite or dyspepsia. Jaundice can occur if stone slips into bile duct thereby blocking the flow of bile (liver juice). Fever may occur if infection becomes severe. But all these symptoms may not be present and others may be present. Hence examination by your doctor is very crucial to diagnose or rule-out gall stone pain. It usually occurs in females of 20 to 40 but no age is immune and many males also have gall stones. Causes- There are many reasons for it and it is usually impossible to find out exact cause in most patients. Too much cholesterol, too much bilirubin, or not enough bile salts in bile can cause gall stones. #STARHospital #ERCP #GallBladderSurgeryNawanshahrPunjabIndia
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