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Cannabinoids (CBD, THC, etc.) are hydrophobic (water-hating, oily) substances and, as such, are not water-soluble. They can, however, be formulated into as water-compatible nanoemulsions and appear water-soluble. Nanoemulsions can be white or translucent. Benefits of Translucent Nanoemulsions: Translucent nanoemulsions are kinetically stable formulations with cannabis/carrier oil droplet sizes well below 100 nanometers. They make it possible to: • infuse water (or another clear beverage) without losing optical clarity; • significantly increase the bioavailability of cannabinoids; • accelerate the onset of medicinal action to about 15 min; • achieve cannabinoid loading of up to 50 mg/ml; • use sterile filtration to remove any microbial contamination. Translucent nanoemulsions can be produced at the rate of about 5 L/hour with our BSP-1200 bench-scale ultrasonic processor and STB-2012 stabilizer package. This rate can be increased to about 20 L/hour with our ISP-3000 industrial-scale ultrasonic processor. The term "water-soluble CBD" has lately been used extensively in the medical cannabis industry. "Water-soluble" means able to homogeneously incorporate into water by separating into molecules or ions (dissolve like sugar, alcohol or salt). Oily substances, however, are repelled by water, which forces them to stay separate from it. CBD, THC and other oils can, however, be made water-compatible if they are formulated as oil-in-water nanoemulsions, which are stable and visually homogeneous oil/water mixtures. Nanoemulsions can be prepared in concentrated forms (tens of mg/ml) that are fully miscible with water and, therefore, appear water-soluble. In addition, nanoemulsions can be made translucent and practically tasteless, which means that they can be mixed into water without compromising its optical clarity or taste. Nano-cannabinoid formulations are simple to make with Industrial Sonomechanics’ patented Barbell Horn Ultrasonic Technology and additive packages. Our high-amplitude ultrasonic processors can continuously produce food- and pharmaceutical-grade cannabinoid nanoemulsions on laboratory, bench and industrial scales, guaranteeing reproducible results and superior quality. Benefits of CBD/THC Nanoemulsions: -Water-compatible: easily mixed into beverages -Translucent, low-taste and safe for consumption -Exceptionally high bioavailability -Fast onset of action and stable blood level -High CBD/THC loading capacity -Enhanced skin permeation for topicals -Long-term product stability -Intra- oral, intra-nasal, pulmonary, transdermal Benefits of Ultrasonic Production: -Tens of liters (thousands of doses) per hour -Extremely small droplet sizes (translucent) -Low surfactant requirements -Emulsifies all cannabinoids and terpenes -No damage to any compounds -Simple, economical and safe processing -Easy equipment setup and maintenance -Direct laboratory-to-production scale-up More information is available at: http://blog.sonomechanics.com/blog/topic/medical-cannabis Contact ISM to request quotation for our ultrasonic processors and stabilizer package NanoStabilizer 201203 at: http://info.sonomechanics.com/contact_us Music: http://www.bensound.com
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Dr. Frank Michalski answers the following questions on CBD for Diabetes; • How can CBD assist with Diabetes or Diabetic symptoms? • Can Type 1 Diabetes also benefit from CBD? • How much CBD should I take for Diabetes? To read more or watch the full interview with Dr. Frank Michalski please visit us at: https://www.cbdbiocare.com/blogs/articles/cbd-for-diabetes-1 #CBDBioCare #CBDforDiabetes #DiabeticSymptoms
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CBD gummies have been gaining popularity as a convenient and tasty way to consume CBD. But have you ever wondered about the science behind CBD gummies? How do they work in the body, and what sets them apart from other methods of CBD consumption? In this article, we will explore the science behind CBD gummies and why they have become a popular choice for many CBD users.
The Endocannabinoid System
To understand how CBD gummies work, it’s essential to first understand the endocannabinoid system (ECS). The ECS is a complex network of receptors, enzymes, and endocannabinoids that help regulate many essential functions in the body, such as mood, appetite, pain sensation, and memory. The ECS plays a crucial role in maintaining homeostasis, or internal balance, within the body. When the ECS is not functioning correctly, it can lead to various health issues.
When you consume CBD gummies, the CBD interacts with the ECS by binding to cannabinoid receptors, namely CB1 and CB2 receptors. CB1 receptors are primarily found in the central nervous system, while CB2 receptors are located in the peripheral nervous system and immune cells. By interacting with these receptors, CBD can help regulate various bodily functions and promote overall wellness.
Unlike THC, another cannabinoid found in cannabis, CBD does not produce psychoactive effects. This means that CBD gummies will not make you feel “high” like THC does. Instead, CBD gummies offer the potential health benefits of CBD without the mind-altering effects of THC, making them a safe and non-intoxicating option for many users.
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One critical factor to consider when choosing a CBD product is its bioavailability, or the amount of CBD that enters the bloodstream and is available for use by the body. The bioavailability of CBD gummies can vary depending on several factors, such as the quality of the product, the dosage, and individual differences in metabolism.
When you consume CBD gummies, the CBD must first pass through the digestive system before entering the bloodstream. This process can take time, as the CBD is broken down by enzymes in the stomach and liver. As a result, the bioavailability of CBD gummies is lower compared to other methods of consumption, such as sublingual tinctures or inhalation.
Despite the lower bioavailability of CBD gummies, many users prefer them because of their discreet and convenient nature. Gummies are easy to take on the go and offer a precise dosage of CBD, making them a popular choice for beginners and experienced users alike. Additionally, the effects of CBD gummies tend to last longer compared to other methods of consumption, providing sustained relief for certain conditions.
Entourage Effect and Full-Spectrum CBD
It’s essential to consider the entourage effect when choosing a CBD product, as it can enhance the therapeutic benefits of CBD. The entourage effect refers to the synergistic interaction between different cannabinoids, terpenes, and other compounds found in the cannabis plant. When these compounds work together, they can have a more significant impact on the body compared to CBD alone.
Full-spectrum CBD gummies contain a variety of cannabinoids, including CBD, THC (at legal levels of 0.3% or less), and other beneficial compounds found in the hemp plant. By consuming full-spectrum CBD gummies, you can experience the entourage effect and potentially maximize the health benefits of CBD. However, it’s essential to consider the legal implications of consuming THC, especially if drug testing is a concern.
On the other hand, broad-spectrum CBD gummies contain all the beneficial compounds found in the hemp plant, except for THC. This allows you to experience the entourage effect without the risk of psychoactive effects from THC. Broad-spectrum CBD gummies are an excellent option for users who want to avoid THC but still benefit from the synergistic effects of multiple cannabinoids and terpenes.
Dosage and Safety Considerations
When taking CBD gummies, it’s crucial to consider the dosage and safety considerations to ensure a positive experience. The ideal dosage of CBD gummies can vary depending on individual factors such as weight, metabolism, and the severity of the condition being treated. It’s always best to start with a low dosage and gradually increase it as needed to find the right balance for your body.
It’s also essential to choose high-quality CBD gummies from reputable brands to ensure safety and efficacy. Look for products that have been tested by third-party laboratories for purity and potency, and that contain accurate information on the label regarding CBD content and other ingredients. Avoid products that make unrealistic health claims or contain harmful additives, as they may not be safe for consumption.
Lastly, consult with a healthcare provider before starting a CBD regimen, especially if you are pregnant, nursing, or have a medical condition. CBD gummies may interact with certain medications, so it’s essential to discuss potential risks and benefits with a healthcare professional before incorporating them into your wellness routine.
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Il team di Cannabiscienza è composto da ricercatori, docenti universitari, medici, farmacisti e consulenti del settore. Cannabiscienza è concentrata su una mission molto chiara: “diffondere l’informazione scientifica internazionale sulla Cannabis Medica e Sistema Endocannabinoide ed agevolarne la comprensione in Italia”. Ci dedichiamo a disseminare la ricerca scientifica sulla Cannabis Medicinale (CM). Pensiamo che diffondere queste informazioni in maniera chiara e semplice possa offrire valore ad un gran numero di cittadini sul nostro territorio: dai pazienti e le loro famiglie, medici & farmacisti, enti ed organizzazioni. Scopri di più: https://cannabiscienza.it/formazione/ #insonnia #sleepdisorder #cantsleep #neuroscienze
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Broad Spectrum CBD vs Full Spectrum CBD: What's the Difference? Blog post: https://www.newphaseblends.com/broad-spectrum-full-spectrum-whats-the-difference/ New Phase Blends CBD Store: https://www.newphaseblends.com/ Most people that are new to the CBD industry, or CBD products, will eventually need to choose between broad spectrum CBD vs. full spectrum CBD products. A third type of CBD product known as a ‘CBD isolate’ also exists. For the purposes of this video, I will stick with discussing the differences between broad spectrum CBD vs. full spectrum CBD. There are a lot of myths and generally incorrect information out there about this topic, and I’ll do my best to set you in the right direction. An interesting thing to keep in mind when it comes to broad vs. full spectrum hemp is there is currently no established regulatory definition of broad vs. full spectrum extracts. A lot of industry leaders believe that the FDA will define the terms officially, once they approve CBD for use as a dietary supplement. As you can imagine, this creates a rather confusing, and annoying, environment for consumers and business owners alike. Don’t worry. You will completely understand the differences between broad vs. full spectrum hemp extract and CBD products after finishing up this video. Read more in the blog...
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