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The Science behind Marijuana (Cannabis), Marijuana mechanism of action. Source of information: National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services. Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images. Voice by: Sue Stern Animation ©Alila Medical Media. All rights reserved. Marijuana, also known as cannabis, among other names, is a preparation of the Cannabis sativa plant - the hemp plant, intended for recreational and medicinal uses. The main psychoactive chemical in marijuana is delta-9-tetrahydro-cannabinol, or THC. The Cannabis plant preparation also contains other compounds that are chemically related to THC, called cannabinoids. THC is chemically similar to a class of substances found naturally in our nervous system called endogenous cannabinoids, or endocannabinoids, of which anandamide is best known so far. The endocannabinoids are part of a newly discovered system named the Endocannabinoid system, or ECS. How the ECS works The ECS acts as a modulator of neurotransmission. When the postsynaptic neuron is activated, endocannabinoids are produced, released, and travel back to the presynaptic neuron where they activate cannabinoid receptors. By doing so, they control what happens next when the presynaptic cell is again stimulated. The general effect is a decrease in the release of neurotransmitters such as GABA or glutamate. In other words, the ECS acts as a “brake”, slowing down neuronal activities, preventing neurons from excessive firing. Some examples of ECS functions include: - Pain modulation: cannabinoids suppress pain signal processing, producing pain relief effects. - Stress and anxiety reduction: The ECS has been implicated in the habituation the body’s response to repeated exposure to restraint stress. - Mood regulation: the ECS promotes “good feeling” by inducing dopamine release in the brain reward pathway. This explains the euphoria, or the “high”, experienced by marijuana users. THC mode of action is however different from other drugs: it induces dopamine release INDIRECTLY by removing inhibitory action of GABA on dopaminergic neurons. The ECS is also involved in many more bodily activities, including appetite, memory, learning, sleeping patterns, immune functions and fertility. So how can marijuana be harmful if it does exactly what our body already does to itself? The endocannabinoids are short-acting transmitter substances. They are synthesized on demand and their signaling is rapidly terminated by specific enzymes. Marijuana users consume a much higher amount of THC. THC is also much more stable and can persist in the body for a longer period of time. THC overwhelms the EC system, overriding normal brain functions. Because cannabinoid receptors are present in many parts of the brain and body, the effects of THC are wide-ranging. It can slow down a person’s reaction time, which could impair driving or athletic skills; disrupt short-term memory and higher thought processes, which could affect learning capabilities and judgment ability. Higher doses of THC may also lead to reverse effects. Consuming marijuana by smoking may also damage the lungs to a similar extent as smoking cigarettes. Long - term effects of THC Substantial evidence from animal research indicates that marijuana exposure can cause long-term adverse changes in the brain. Long-term effects of marijuana in human are still debatable mostly due to difficulties of conducting research in human beings. Medical uses of marijuana While recreational use of marijuana is without doubt harmful, the Cannabis plant may be a valuable source of medicines. Currently, the two main cannabinoids from the marijuana plant that are of medical interest are THC and cannabidiol, or CBD. These chemicals are used to increase appetite and reduce nausea in patients undergoing cancer chemotherapy. They may also be useful in reducing pain and inflammation, controlling epileptic seizures, and possibly even treating autoimmune diseases and cancers.
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Watch the “Ultimate Human Podcast” every Tuesday & Thursday at 9AM EST: YouTube: https://bit.ly/3RPQYX8 Podcasts: https://bit.ly/3RQftU0 Connect with Gary Brecka: Instagram: https://bit.ly/3RPpnFs TikTok: https://bit.ly/4coJ8fo X.com: https://bit.ly/3Opc8tf Facebook: https://bit.ly/464VA1H LinkedIn: https://bit.ly/4hH7Ri2 Website: https://bit.ly/4eLDbdU Merch: https://bit.ly/4aBpOM1 Newsletter: https://bit.ly/47ejrws Ask Gary: https://bit.ly/3PEAJuG The Ultimate Human with Gary Brecka Podcast is for general informational purposes only and does not constitute the practice of medicine, nursing or other professional health care services, including the giving of medical advice, and no doctor/patient relationship is formed. The use of information on this podcast or materials linked from this podcast is at the user’s own risk. The Content of this podcast is not intended to be a substitute for professional medical advice, diagnosis, or treatment. Users should not disregard or delay in obtaining medical advice for any medical condition they may have and should seek the assistance of their health care professionals for any such conditions.
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Améo Entune CBD Squares are the best CBD product in the marketplace! Try them today: https://www.zijainternational.com/shop/cart?referral=1623255&products%5B177384%5D=1&country=US CBD is the master regulator. It helps “tune” up the rest of the systems-nervous, endocrine, cardiovascular, etc. Ameo Entune CBD Squares are Full-Spectrum Hemp-Derived CBD Squares. Dual Release Transdermal Squares. Water-Soluble Hemp CBD Powder for swift ability help smooth muscles, aid overall well-being and more. Hemp CBD oil to work within cells to help support energy function. Designed to be worn for 24 hours! Waterproof. Cannabidiol (CBD) influences receptors found throughout the body that are associated with multiple cellular and physiological responses to hormones, neurotransmitters, and environmental stimulants. Through this interaction with cell receptors, CBD tunes the endocannabinoid system to promote calm feelings, aid normal cognitive function, encourage a positive mood, support restful sleep, and quiet everyday aches, leading to improved overall well-being! Soothes mind to promote a more restful and sound sleep. Relaxes mind to help encourage calm, collected feelings during periods of stress or nervousness, while maintaining greater focus. Supports Key Body Systems. Helps support multiple key body systems to promote a general sense of well-being. AIds Immune Equalibrium. Fast Acting Comfort. Influences the Endocannabinoid System for fast acting comfort. The Lot # on my Entune Squares is: 9999758. Enter that number here: www.zijadifferrence.com to learn more about that exact batch! Hemp derived CBD with .3% or less THC is federally legal with the passing of the Farm Bill in December 2018. Learn more about all of my Zija products here: http://marcyvandenburg.myzija.com Join my Essential Oil Community here: https://www.facebook.com/groups/1927850464201046/ Want to start your own YouTube channel? Learn from the best-this is who I follow: https://courses.seancannell.com/a/7802/PzF9ziuP DISCLAIMER: This video and description contains affiliate links which means that if you click on one of the product links I may earn a small commission at no extra cost to you #ameocbdpatch #zijacbdpatch #ameoessentialoils
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In this study club webinar, Dr. Kent Smith dives into the hot topic of CBD oils, including the latest science and research, and their applications for patients that present with insomnia, anxiety, & pain.
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Get the Super Simple App! ► http://bit.ly/TheSuperSimpleApp Let's see what the potatoes do for fun in this Super Simple version of the classic "One Potato, Two Potato" choosing rhyme. 🎶 One potato, two potatoes, three potatoes, four. Five potatoes, six potatoes, seven potatoes, more! 🎶 PARENTS AND TEACHERS: Thank you so much for watching Super Simple Songs with your families and/or students. Here are some other places to find great Super Simple content: ► SUPER SIMPLE APP -- http://bit.ly/TheSuperSimpleApp Be the first to watch new Super Simple videos in the Super Simple App! Ad-free and designed for young learners. ► YOUTUBE KIDS -- http://bit.ly/You-Tube-Kids Designed to make it safer and simpler for young ones to watch online video, YouTube Kids includes a suite of parental controls so you can tailor the experience to suit your family’s needs. ► AMAZON VIDEO Are you an Amazon Prime member? Watch Super Simple videos ad-free on Amazon Prime Video. Just search for “Super Simple.” FREE SUPER SIMPLE TEACHING RESOURCES: http://bit.ly/SSFree-Resources SOCIAL MEDIA: Super Simple Newsletter Sign Up: http://bit.ly/SuperSimpleSignUp Facebook: http://bit.ly/SuperSimpleFacebook Instagram: http://bit.ly/SuperSimpleInsta Twitter: http://bit.ly/SuperSimpleTwitter Pinterest: http://bit.ly/SuperSimplePinterest ********* Lyrics: [Sing] One potato Two potatoes Three potatoes Four Five potatoes Six potatoes Seven potatoes More One potato Two potatoes Three potatoes Four Five potatoes Six potatoes Seven potatoes More [Chant] One potato Two potatoes Three potatoes Four Five potatoes Six potatoes Seven potatoes More [Sing] One potato Two potatoes Three potatoes Four Five potatoes Six potatoes Seven potatoes More One potato Two potatoes Three potatoes Four Five potatoes Six potatoes Seven potatoes More [Chant] One potato Two potatoes Three potatoes Four Five potatoes Six potatoes Seven potatoes More ********* © Skyship Entertainment Company. All rights reserved. Super Simple, Super Simple Songs, Noodle & Pals, Finny the Shark, Caitie’s Classroom, Rhymington Square, the Bumble Nums, Carl’s Car Wash and associated logos are trademarks of Skyship Entertainment Company. #supersimple #nurseryrhymes #kidssongs #childrensmusic #funlearningactivities
