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Scientists have shown that an active ingredient of cannabis significantly upregulates autophagy, extending both lifespan and healthspan in C. elegans nematode worms and demonstrating benefits to mouse neurons. Two of the most well-known components of marijuana are tetrahydrocannabinol, or THC, and cannabidiol, or CBD. They have the same atomic composition, but differ in structure. THC provides the high that is often associated with marijuana use. CBD, on the other hand, is considered benign and seems to possess antipsychotic, pro-cognitive, anti-inflammatory, anti-seizure, and antioxidant properties. In June 2018, the FDA approved Epidiolex, the first CBD-based prescription medication, for rare forms of epilepsy, and later for the treatment of some seizures. However, the research into both compounds is still in its infancy. In this new study, scientists dived deeper into the workings of CBD using C. elegans nematode worms, which is considered a good model for initial studies, including in geroscience. Previous research has shown that CBD can increase lifespan in C. elegans and zebrafish, but the mechanism had remained unknown. Another study found that CBD induces autophagy in cultured neuronal cells. In this new study, the researchers attempted to investigate the relationship between these two effects. Autophagy is the process of clearing away various cellular debris, such as misfolded proteins and dysfunctional organelles. Unsurprisingly, this maintenance system appears to be very important for health and longevity in numerous model organisms and in humans. The CBD treatment greatly increased autophagic activity in several tissues and cell types, most drastically by 78% in neurons. The researchers then validated those findings in vitro on several types of cells, including mouse primary hippocampal neurons. Importantly, impaired autophagy in the brain is considered a major cause of Alzheimer’s disease. Worms on CBD lived significantly longer than controls. The researchers also measured the worms’ healthspan. Many interventions that prolong lifespan in C. elegans often lead to functional impairment, such as decreased motility. Three popular health metrics in C. elegans that decline with age are pharyngeal pumping rate, reproductive capacity, and locomotion, and all three were significantly restored, rather than impaired, by CBD treatment. The gene SIRT1 has been a popular object of study in geroscience. One of its roles is a mediator of autophagy. By knocking out SIRT1 in mouse neurons, researchers were able to obliterate many of the benefits of CBD, pointing at a crucial role of SIRT1 in mediating CBD-induced effects. This study expands our understanding of CBD's effects, linking them to autophagy, an important process that keeps popping up on geroscientists' radars. It is encouraging that CBD demonstrates the strongest pro-autophagy effect in neurons, making it a potential anti-Alzheimer’s drug. Obviously, the fact that CBD increases autophagy in worms does not mean that using marijuana makes humans healthier, and we’ll need to see human trials on CBD and other compounds. SOURCES AND FURTHER READING ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Cannabidiol induces autophagy and improves neuronal health associated with SIRT1 mediated longevity - https://pubmed.ncbi.nlm.nih.gov/35445360/ Effect of Cannabidiol on the Long-Term Toxicity and Lifespan in the Preclinical Model Caenorhabditis elegans - https://pubmed.ncbi.nlm.nih.gov/33998871/ Developmental exposure to cannabidiol (CBD) alters longevity and health span of zebrafish (Danio rerio) - https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7205952/ Cannabidiol induces autophagy via ERK1/2 activation in neural cells - https://www.nature.com/articles/s41598-021-84879-2 EPIDIOLEX - https://youtu.be/zepKBzlKzdY FOOTAGE, IMAGES, AND MUSIC CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Stock footage & Images : Videoblocks.com, Shutterstock.com Music: "Elastic Vibe" by Ziv Moran PRODUCTION CREDITS ⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺⎺ Host, Producer, & Editor - Ryan O’Shea Writer - Arkadi Mazin Art - Mattijs Vonk, Tim Maupin Executive Producer - Keith Comito #CBD #Science #Longevity
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In this video, we will discuss what CBD and THC is. We will talk about the differences between the two, how they interact with the body and what they can be used for. CBD stands for cannabidiol and can be made from hemp or marijuana. CBD has no psychoactive effect known as the high/out of body experience. THC stands for tetrahydrocannabinol and is made from marijuana plants. It can be produced at up to 30% in liquid form. THC does have a psychoactive effect. CBD is easier to metabolize than THC because when THC is metabolized it produces 11-OH-THC. This is what creates the high sensation. It is also much more difficult to metabolize when taken as an edible than when it is smoked. Edibles can also increase the psychoactive effect of THC. Endo-cannabinoids are neurotransmitters which are naturally produced in the brain, and create the feeling of happiness and laughter from anandamide. Anandamide can be increased and activate the CB1 and CB2 receptors with THC. CBD has a more difficult time binding to the CB1 and CB2 receptors, but leaves neurotransmitters in the synapse for longer allowing them to bind to other receptors and other channels more easily. CBD and THC can be used for tumor regression and some cancer prevention. Please note that this does not apply to all types of cancer. They can also help degrade amyloid-beta plaque which helps with dementia, Alzheimer's and cognitive function. Additionally, they can help with pain, anxiety, addiction, appetite, sleep, nausea and vomiting (specifically THC), and seizures in people with epilepsy or autism. Pure THC has shown to reduce PTSD symptoms and help regulate sleep. Please see a professional before using THC or CBD. At Turnpaugh Health and Wellness Center, Dr. Regina Smith is certified to prescribe medical marijuana and is excellent at monitoring patients so they can reap the benefits of THC without causing damage.
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Our CBD products are strictly organic with no chemical additives, while we grow our hemp plant under the best environmental conditions in Colorado. The manufacturing process follows a strict method that retains all the valuable properties of the hemp plant while eliminating most occurrences of THC. To ensure the quality of our products, they are lab tested and confirmed to be GMO-free, leading us to have Good Manufacturing Practice Certification. https://www.reefinedcbd.com/
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Using Topical over gummy for pain relief is gaining popularity as an effective solution for managing chronic pain. In this video, we explore how gummies work, topicals can be applied, their benefits, some major pain relief tips everyone leaves out and if they are the right choice for effective pain relief option. From 10 years experience, with to real user testimonials, I cover what you need to know about topical over gummies for pain relief hacks you should know. Whether you suffer from a chronic pain or occasional discomfort, these natural pain methods could be a game changer. Don't miss out on this short guide to finding relief with topical over gummies! If you want to see more, 🔔Subscribe to the @cbdheadquarters channel 📺 https://www.youtube.com/channel/UCTkQHpucL8dPE5Sa0HaCmNw?sub_confirmation=1 Thanks for watching the video "Optimal Duration for Using CBD Cream for Pain Relief" #TopicalGummy #PainRelief #TopicalOverGummy #PainManagement #ChronicPain #GummyRelief #NaturalPainRelief #PainReliefSolution #GummiesForPain #EffectivePainRelief All cannabis-related content is strictly for educational and entertainment purposes ONLY. We do not condone or encourage anyone to experiment with cannabis without first consulting your physician and ensuring compliance with applicable laws in your area.
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Unlocking the Benefits of Medallion CBD Gummies
In recent years, the wellness industry has witnessed an incredible surge in the popularity of cannabidiol (CBD), a natural compound derived from the cannabis plant that is lauded for its potential health benefits. Among various forms of CBD consumption available, Medallion CBD Gummies have carved a niche for themselves, appealing to both seasoned CBD users and newcomers alike. The allure of these gummies lies not only in their delicious flavors and convenient form but also in their potential to promote overall wellness. As more users share their experiences, the reported benefits have fueled a growing interest in how these gummies might help individuals manage various health conditions effectively.
Medallion CBD Gummies are formulated to provide a precise dosage of CBD in a tasty, easy-to-consume gummy form. They contain high-quality CBD extract sourced from hemp plants, along with other natural ingredients, ensuring that consumers know exactly what they are ingesting. This transparency is particularly appealing in an industry where product quality can significantly vary. Each gummy typically contains a consistent amount of CBD, making it easier for users to monitor their intake and adjust as necessary, depending on their unique wellness goals.
The use of CBD has been associated with a variety of health benefits, including pain relief, anxiety reduction, and improved sleep. However, as with any supplement, the effectiveness can vary from person to person. Medallion CBD Gummies have been extensively reviewed by customers, many of whom report positive results. The gummies’ appealing textures and flavors, combined with the potential for health enhancement, present them as an attractive option for those looking to incorporate CBD into their daily regime. In this article, we will explore five key wellness benefits of Medallion CBD Gummies as highlighted by customer testimonies, illuminating how these gummies could be a valuable addition to your health and wellness journey.
Enhancing Sleep Quality
One of the most commonly reported benefits of Medallion CBD Gummies is their potential to improve sleep quality. Many users have expressed that they struggle with restless nights, whether due to stress, anxiety, or other sleep disorders. The natural calming properties of CBD may help alleviate these issues, allowing for a more restful and rejuvenating night’s sleep. Customer testimonials frequently mention that taking a gummy before bedtime has significantly reduced the time it takes them to fall asleep, enhancing both the quantity and quality of their sleep.
The mechanism through which CBD may improve sleep is linked to its interaction with the body’s endocannabinoid system, which plays a crucial role in regulating various functions, including sleep-wake cycles. Customers have noted that Medallion CBD Gummies help to alleviate anxiety and racing thoughts that often accompany insomnia. By promoting relaxation and reducing discomfort, individuals can experience a more consistent sleep pattern, which is essential for overall health and well-being.
Moreover, the ease of use and pleasant taste of these gummies make them an appealing nighttime ritual. Instead of turning to sleep medications, which can have harsh side effects and the potential for dependency, consumers find solace in a natural alternative. The positive feedback surrounding sleep improvement showcases Medallion CBD Gummies as a potential go-to solution for anyone looking to enhance their nightly rest and embrace a healthier sleep foundation.
Relief from Anxiety and Stress
Another remarkable benefit that Medallion CBD Gummies provide, as highlighted through customer reviews, is stress and anxiety relief. In today’s fast-paced world, anxiety and stress have become common concerns for many people. Those who have integrated these gummies into their routines often report a noticeable decrease in their overall stress levels and an improved ability to manage daily challenges. Testimonials commonly reflect a sense of calm that follows the consumption of these gummies, allowing individuals to navigate their day with a more positive mindset.
The effectiveness of CBD in managing anxiety is attributed to its effect on neurotransmitters in the brain, particularly serotonin. By promoting a balanced mood and emotional stability, Medallion CBD Gummies empower consumers to confront their daily anxieties, whether they are work-related, social situations, or personal challenges. Users often describe feeling more grounded and less overwhelmed, leading to an improved quality of life and increased productivity.
This aspect of wellness is particularly important as mental health awareness grows, and more individuals seek holistic and natural solutions rather than traditional pharmaceuticals. The positive feedback from customers underscores the capability of Medallion CBD Gummies to provide a sense of relief, allowing them to engage more fully in their lives without the burdens of excessive stress and anxiety. Accompanied by their tasty flavors, these gummies present a delightful option for those seeking mental wellness support.
Promoting Pain Relief and Inflammation Reduction
Medallion CBD Gummies are also celebrated for their potential to alleviate pain and reduce inflammation, another common theme in customer reviews. For those dealing with chronic pain conditions, including arthritis, back pain, and muscle soreness, these gummies could offer a gentle yet effective alternative to traditional pain management methods. Many users have reported experiencing a significant reduction in discomfort after integrating these gummies into their daily regimen, contributing to improved mobility and overall physical performance.
The anti-inflammatory properties of CBD play a major role in its ability to relieve pain. It works by interacting with the body’s endocannabinoid system, which helps to regulate pain perception. Customers often note that after consuming Medallion CBD Gummies, they experience less stiffness and swelling, which is particularly beneficial for athletes and active individuals who need to recover after intense physical activity. This aspect of CBD’s effectiveness makes it an appealing option for anyone looking to maintain an active and healthy lifestyle without the side effects often associated with conventional pain relief medications.
Furthermore, the positive testimonials reflect not just physical relief but also an emotional uplift as users regain control over their bodily discomfort. The combination of ease of use, pleasant taste, and notable effectiveness makes Medallion CBD Gummies a popular choice among individuals seeking pain relief. The versatility of these gummies positions them as a resource for anyone looking to enhance their quality of life by alleviating pain and promoting a healthy inflammatory response.
Supporting General Wellness and Health
As part of the holistic benefits of Medallion CBD Gummies, many users report improvements in their overall well-being. This encompasses a range of factors including enhanced vitality, better focus, and increased energy levels throughout the day. Customer reviews indicate that these gummies not only target specific ailments but contribute positively to a healthier lifestyle in general. The convenient delivery method and natural composition of the gummies support users in meeting their wellness goals.
Regular consumption of Medallion CBD Gummies has been associated with improved mood, which directly influences daily performance and quality of life. Customers have emphasized how the gummies help them approach their day with a more positive attitude, leading to a boost in overall productivity and satisfaction. The synergistic effect of CBD’s role in promoting balance within the body aids users in maintaining a more consistent energy level, which is crucial for anyone managing a busy lifestyle.
This focus on holistic health also extends to the gummies being a part of a healthier lifestyle through encouraging self-care practices. The act of taking a gummy can serve as a mindfulness moment, allowing individuals to pause and enjoy a tasty treat while being conscious of their health. This interaction between self-care and wellness highlights the potential of Medallion CBD Gummies to play an integral role in inspiring individuals toward a more aware and health-conscious way of living.
Ease of Incorporation into Daily Life
One of the most significant advantages of Medallion CBD Gummies is their ease of incorporation into daily routines. Unlike oils or capsules, gummies come in a flavorful gummy format, making them not just effective but enjoyable to consume. This user-friendly aspect is frequently highlighted in customer testimonials, as individuals appreciate the convenience without sacrificing the potential benefits of CBD. Whether at home, work, or on-the-go, these gummies provide a straightforward way to include CBD in one’s diet.
Many customers have noted that the tasty flavors encourage regular use, contributing to better consistency in their wellness routines. The attractiveness of these gummies often leads to users enjoying them as a delightful treat, ensuring compliance with their CBD intake without hassle. The portable packaging allows individuals to carry the gummies wherever they go, making it easy to maintain their regimen even amidst a busy lifestyle.
The user-friendly nature of Medallion CBD Gummies not only promotes adherence to daily health goals but also reinforces the notion of making wellness enjoyable rather than a chore. This shift in perspective empowers more individuals to explore CBD and its myriad benefits, further expanding the reach of natural wellness solutions in their lives. The collective experiences of customers affirm how these delightful gummies can seamlessly integrate into a variety of lifestyles while offering a range of health enhancements.
Conclusion and FAQ
Medallion CBD Gummies have gained popularity within the wellness community for good reason. Customers have enthusiastically shared their experiences, highlighting the range of potential benefits that these gummies can provide. From enhancing sleep quality to managing anxiety and pain relief, the collective testimonials paint a picture of a versatile wellness product that resonates with many seeking natural solutions to common health challenges. Their enjoyable flavor and straightforward dosage format further contribute to their appeal, allowing consumers to prioritize their health without added stress.
For those curious about integrating Medallion CBD Gummies into their wellness journey, several frequently asked questions emerge. One common inquiry revolves around the source of CBD in these gummies. Medallion sources its CBD from high-quality hemp plants, ensuring that users receive a premium product. Additionally, potential consumers often ask about the proper dosage. Customer reviews suggest starting with one gummy to gauge individual response before adjusting as necessary. It is always wise to consult a healthcare professional before introducing new supplements into your routine.
Another often-discussed topic accompanies side effects. While CBD is generally considered safe, some users report mild side effects such as drowsiness or changes in appetite. Understanding that individual responses can vary is critical. Therefore, monitoring how your body reacts is pertinent, especially if you are new to CBD products. Medallion CBD Gummies present a novel option for individuals seeking supplemental support for their wellness needs. By embracing the insights of customers who share their reviews, we can appreciate the potential of CBD-infused gummies as an ally in promoting holistic health and well-being.
