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Importance of Decarboxylation for Cannabis Professor DeBacco Research Article ALEKSANDROV, M., & JANEVIK IVANOVSKA, E. (2022). THE ROLE AND IMPORTANCE OF THE DECARBOXYLATION PROCESS IN THE PRODUCTION OF QUALITY FULL-SPECTRUM CANNABIS EXTRACT FOR MEDICINAL PURPOSES. International Journal of Medical Sciences, 7(13-14), 119-128. https://eprints.unite.edu.mk/963/ What is Decarboxylation? All cannabinoids contained within the trichomes of raw cannabis flowers consists of cannabinoids in their acidic form and have an extra carboxyl ring or group (-COOH) attached to their chain. Decarboxylation (or “decarbing”) is where raw cannabis is heated so that the chemical structure of the acid cannabinoids changes to a neutral (non-acid) form. Acidic to Neutral Form Conversion When one states that cannabinoids are in their “acidic form”, they are referring to the chemical structure of the compound itself. A cannabinoid in its acidic form has a carboxyl group (-COOH) attached and the neutral forms, will have this carboxyl group removed. Acid = Raw plant material Neutral = Decarboxylated compound Chemical Structure Changes Transforming cannabinoid acids into their neutral forms, need to remove the carboxyl group. The weak bond holding the carboxyl group can be broken by a combination of heat and time. Why Does Cannabis need Carboxylation? This process essentially converts the chemicals into an “active” form by increasing the bodies ability to absorb and bind to the molecules. Essentially the body can use the “active” form. Carboxylation happens naturally when the plant material is ignited. Importance of Decarboxylation: THCA vs THC While THCA is the non-psychoactive (not decarboxylated form) precursor to THC (the decarboxylated form), it does not bind to the CB1 and CB2 receptors. Note: THCA binds with other cannabinoids receptors in the endocannabinoid system. Although THCA possesses therapeutic effects, like anti-inflammatory and neuroprotective qualities, it is not in its most beneficial or psychoactive form. Decarboxylation Requires Heat and Time The two main catalysts for decarboxylation to occur are heat and time. Drying and curing cannabis over time will cause partial decarboxylation to occur. While heat is needed to decarboxylate the acids into the active form of cannabinoids our bodies can use, extreme temperatures can destroy many of the important plant materials that contribute to positive health outcomes, like terpenes. Use Minimal Temperature to Preserve Terpenes Cannabis Trim Trim is what is removed from the final flower after harvest. Trim includes sugar leaves, bits of cut-off buds, and knocked off trichomes, or kief. Kief Explained When trichomes dry and break off of the plant, they become kief. Kief, because it has oxidized and loses its freshness when separated from the plant buds, usually has a darker color than trichomes, ranging from light gold to brown. It has a powdery appearance and a texture that is somewhat sticky, though less so than trichomes on a bud. Kief tends to decarb faster than an intact flower. Other Factors of Variability… Variety of Cannabis Used Each type of cannabis contains different amounts and ratios of different cannabinoids and terpenes which impact the optimum decarboxylation time and temperatures. This can also be impacted by the physical structure of the flower Age (Freshness) of Product There will be noticeable differences in the final product depending on the age (freshness) of the material you start with. Remember: The decarboxylation process only converts the acidic form to the bioactive neutral form, it does not “create” the CBD or THC molecule. If the flower consistency is widely variable grinding up the plant material will increase the uniformity of the decarboxylation process. General Key Points Need to have in mind that, at higher temperatures, Kief and Hash tend to decarboxylate faster than dried flowers. High CBD strains tend to decarboxylate a bit slower than those with high THC content Three Main Decarboxylating Factors for Cannabis The most important parameters to perform a good decarboxylation process are… Time (duration) Temperature Quality decarboxylation equipment Suggestions for Decarboxylating Your Cannabis From the review of published literature data… Highest concentration of THC (about 15 mg/g) is obtained when the material is decarboxylated at 122°C for 27 minutes. Converting CBDA to CBD, a higher temperature is required, about 150°C, for about 30 minutes. To decarboxylate Kief or Hash in an oven, bake it for 10 minutes at 300°F (149°C). Link to Lecture Slides: https://drive.google.com/file/d/1l4M8JxgL0GUVZO8Cbr15ncUTSSa7QduO/view?usp=drive_link *Due to the description character limit the full work cited for "Importance of Decarboxylation for Cannabis" can be viewed at... https://docs.google.com/document/d/1d7MFDC65xVjxHVmaqPvKlzLVNLidOfyw/edit?usp=drive_link&ouid=104237452697237972847&rtpof=true&sd=true
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Condor CBD Gummies have been gaining popularity as a natural alternative for managing various health issues, including anxiety, pain, and insomnia. As more people turn to CBD products for relief, it’s important to know what real users have to say about their experiences with these gummies. In this article, we’ll unpack user reviews to provide insights into the outcomes people have had with Condor CBD Gummies.
User Experiences: Anxiety Relief
Many users have reported significant relief from anxiety after using Condor CBD Gummies. They have found that the gummies help them feel more calm and relaxed, reducing the symptoms of anxiety in a natural way. One user shared, “I have struggled with anxiety for years, but since I started taking Condor CBD Gummies, I have noticed a significant improvement in my mood and overall well-being.”
Another user mentioned, “I take the gummies whenever I feel anxious, and they help me feel more grounded and at ease. I no longer rely on prescription medications to manage my anxiety, thanks to these gummies.”
Overall, the consensus among users is that Condor CBD Gummies are effective in providing relief from anxiety without any notable side effects. Users appreciate the natural approach to managing their symptoms and find that the gummies are convenient and easy to incorporate into their daily routine.
User Experiences: Pain Management
For individuals dealing with chronic pain, Condor CBD Gummies offer a promising solution. Users have reported a reduction in pain levels and an improved quality of life after using these gummies. One user shared, “I suffer from arthritis, and the pain can be debilitating at times. Since I started taking Condor CBD Gummies, I have experienced a noticeable decrease in pain and inflammation.”
Another user mentioned, “I use the gummies after my workouts to help with muscle soreness, and they work wonders. I no longer need to rely on over-the-counter pain medications to manage my pain.” Users appreciate the long-lasting relief provided by the gummies and find that they are a natural and effective alternative to traditional pain management methods.
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Overall, user experiences with Condor CBD Gummies for pain management have been overwhelmingly positive, with many users reporting a significant improvement in their pain levels and overall quality of life. The gummies offer a natural and holistic approach to managing pain without the need for harsh medications or treatments.
User Experiences: Sleep Support
Good sleep is essential for overall health and well-being, and Condor CBD Gummies have been shown to help users achieve a restful night’s sleep. Users struggling with insomnia or sleep disturbances have found relief by incorporating these gummies into their bedtime routine. One user shared, “I have always had trouble falling asleep and staying asleep, but since I started taking Condor CBD Gummies, I have noticed a significant improvement in my sleep quality.”
Another user mentioned, “The gummies help me relax before bedtime and stay asleep throughout the night. I wake up feeling refreshed and rejuvenated, which has made a big difference in my daily life.” Users appreciate the gentle and natural sleep support provided by the gummies, without the grogginess or side effects commonly associated with traditional sleep aids.
Overall, user experiences with Condor CBD Gummies for sleep support have been positive, with many users reporting improved sleep quality and a more restful night’s sleep. The gummies offer a non-habit forming and natural solution to sleep disturbances, making them a popular choice among individuals looking to improve their sleep patterns.
