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The Science behind Marijuana (Cannabis), Marijuana mechanism of action. Source of information: National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services. Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images. Voice by: Sue Stern Animation ©Alila Medical Media. All rights reserved. Marijuana, also known as cannabis, among other names, is a preparation of the Cannabis sativa plant - the hemp plant, intended for recreational and medicinal uses. The main psychoactive chemical in marijuana is delta-9-tetrahydro-cannabinol, or THC. The Cannabis plant preparation also contains other compounds that are chemically related to THC, called cannabinoids. THC is chemically similar to a class of substances found naturally in our nervous system called endogenous cannabinoids, or endocannabinoids, of which anandamide is best known so far. The endocannabinoids are part of a newly discovered system named the Endocannabinoid system, or ECS. How the ECS works The ECS acts as a modulator of neurotransmission. When the postsynaptic neuron is activated, endocannabinoids are produced, released, and travel back to the presynaptic neuron where they activate cannabinoid receptors. By doing so, they control what happens next when the presynaptic cell is again stimulated. The general effect is a decrease in the release of neurotransmitters such as GABA or glutamate. In other words, the ECS acts as a “brake”, slowing down neuronal activities, preventing neurons from excessive firing. Some examples of ECS functions include: - Pain modulation: cannabinoids suppress pain signal processing, producing pain relief effects. - Stress and anxiety reduction: The ECS has been implicated in the habituation the body’s response to repeated exposure to restraint stress. - Mood regulation: the ECS promotes “good feeling” by inducing dopamine release in the brain reward pathway. This explains the euphoria, or the “high”, experienced by marijuana users. THC mode of action is however different from other drugs: it induces dopamine release INDIRECTLY by removing inhibitory action of GABA on dopaminergic neurons. The ECS is also involved in many more bodily activities, including appetite, memory, learning, sleeping patterns, immune functions and fertility. So how can marijuana be harmful if it does exactly what our body already does to itself? The endocannabinoids are short-acting transmitter substances. They are synthesized on demand and their signaling is rapidly terminated by specific enzymes. Marijuana users consume a much higher amount of THC. THC is also much more stable and can persist in the body for a longer period of time. THC overwhelms the EC system, overriding normal brain functions. Because cannabinoid receptors are present in many parts of the brain and body, the effects of THC are wide-ranging. It can slow down a person’s reaction time, which could impair driving or athletic skills; disrupt short-term memory and higher thought processes, which could affect learning capabilities and judgment ability. Higher doses of THC may also lead to reverse effects. Consuming marijuana by smoking may also damage the lungs to a similar extent as smoking cigarettes. Long - term effects of THC Substantial evidence from animal research indicates that marijuana exposure can cause long-term adverse changes in the brain. Long-term effects of marijuana in human are still debatable mostly due to difficulties of conducting research in human beings. Medical uses of marijuana While recreational use of marijuana is without doubt harmful, the Cannabis plant may be a valuable source of medicines. Currently, the two main cannabinoids from the marijuana plant that are of medical interest are THC and cannabidiol, or CBD. These chemicals are used to increase appetite and reduce nausea in patients undergoing cancer chemotherapy. They may also be useful in reducing pain and inflammation, controlling epileptic seizures, and possibly even treating autoimmune diseases and cancers.

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What is up Guilty FAMMM!!! Brenden and Jake back back back againnn with another reviewww!! Today we have got Ghost's Scary Potent Reaper Gummies in the Gremlin Gummy flavor!!! Super excited for this review as we absolutely love THCP and Ghost is a solid company!!!! Thank you for tuning in we will try our best to visit the comments as much as possible! Always remember shop Guilty Vibez and stay groovy y'all!! Big Big shoutout to good ol Ghost for sending up this bag for us to show off!!! We hope you like the video!! THCP is legal at the federal level, thanks to the 2018 Farm Bill, which legalized hemp-sourced cannabinoids that contain no more than 0.3% of Delta-9 THC by dry weight. However, every state still has the right to limit access to THCP products. PSA...anything you guys want us to review/check out on camera, let us know down below in the comments. However if you'd rather come on down and have a chat with either of us about a product or review at any of the three locations you are more than welcome! Instagram - https://www.instagram.com/ghost.hemp/ #Smokeshop #ghosthemp #THCP #scarypotent #THCP #Guiltyvibez #gremlingummy #vibing #goodvibes #groovy #edibles #Smokeshopreview #thishitsdifferent #youmatter

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Two bills proposed this session have to do with regulating hemp. For more Local News from WOWT: https://www.wowt.com/ For more YouTube Content: https://www.youtube.com/channel/UCHyFuvaP40uvL0RE48NbsMw

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Pet parents, let’s face it—finding the right CBD for your furry friends can feel like navigating a maze. With the CBD market booming, not all products are created equal. Here's how to cut through the noise and make informed choices to keep your pets happy and healthy! ✨ Top Tips for Buying Pet CBD: 1️⃣ Choose Full Spectrum: Look for CBD made with full spectrum hemp extract, containing all-natural plant compounds (including trace THC) for maximum benefits. 2️⃣ Go Organic & Local: Select products made from organically grown, U.S.-sourced hemp to avoid pesticides or harmful chemicals. 3️⃣ Demand Transparency: Only trust brands that provide third-party lab results (COAs) verifying potency and purity. 4️⃣ Prioritize Quality Extraction: Products extracted from the flower using CO2 yield richer, safer compounds than cheaper alternatives. 5️⃣ Check Potency: Ensure each dose contains at least 3mg of CBD to be effective. 6️⃣ Think Bioavailability: Oils absorbed through the gums are more efficient than treats or capsules. Bonus: Look for organic MCT or hemp seed oil for better absorption! 7️⃣ Avoid Unnecessary Ingredients: Steer clear of artificial flavors, preservatives, and harmful additives like xylitol. 8️⃣ Choose Pet-Specific CBD: Human CBD products aren’t designed for pets—stick to formulations tailored for their needs. 9️⃣ Read Reviews: Learn from other pet parents’ experiences before buying. 🔟 Trust Reputable Brands: Do your research, ask questions, and ensure the brand stands by its quality and customer support. 💡 Remember: High-quality CBD won’t be the cheapest option. If a deal seems too good to be true, it probably is. 🔗 Drop your favorite CBD questions below or visit our website to learn more about safe, effective products for your pets! 🐕‍🦺 Let’s keep our four-legged family members thriving into the new year! #PetCBD #NaturalWellness #HappyHealthyPets #CBD #cbdforpets #hempforpets #hempfordogs #hemp #dog #doglove #doglover #doglife #dogshort www.cbddoghealth.com www.angelaardolino.com Join our FB Support Group! https://www.facebook.com/groups/HolisticPetAdvice/

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