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COLUMBUS, Ohio (WKRC) - Ohio lawmakers consider lifting the state's ban on growing hemp and selling CBD products that are derived from it. A measure introduced Tuesday in the Ohio Senate would follow the 2018 federal farm bill, which lifts the nationwide prohibition on hemp but left regulations up to individual states. Current Ohio law does not differentiate between hemp and marijuana, and that has led to stores pulling CBD products from their shelves. Other products can be made from hemp, including rope and car parts.
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CBD is one of a class of compounds known as cannabinoids, which are found in the cannabis plant. Unlike THC (the main psychoactive component of cannabis), CBD is not thought to have intoxicating effects. It is, however, believed to interact with the nervous system. In this video, I discuss what we know about CBD’s mechanism of action and its potential in treating various conditions like epilepsy and anxiety. TRANSCRIPT: CBD is one of a class of compounds known as cannabinoids, which are found in the cannabis plant. Unlike THC (the main psychoactive component of cannabis) CBD is not thought to have intoxicating effects. It is, however, believed to interact with the nervous system, which may enable it to modulate the effects of thc as well as have actions of its own. CBD is chemically similar to THC, but it does not have the same mechanism of action, and some evidence suggests it may even interfere with some of the actions of THC. One way it may do this is by binding to receptors that THC binds to known as CB1 receptors, but instead of activating them, causing a change in the receptor that reduces THC’s ability to interact with it. This type of effect is known as negative allosteric modulation, and it may enable CBD to mitigate some of the adverse effects of THC, like anxiety. Other research, however, suggests CBD can enhance certain effects of THC, and CBD is also thought to act at a number of other targets besides the CB1 receptor. For example, CBD is believed to activate serotonin receptors and may increase levels of a natural cannabinoid called anandamide by blocking anandamide reuptake and inhibiting the enzymatic breakdown of anandamide. Overall, although a number of targets for CBD have been identified, its mechanism of action is still poorly understood. CBD is generally well-tolerated, but some have raised concerns about the need for more research before we can be confident about its safety in all populations. CBD, however, is not thought to have potential for abuse, and some believe it does have potential for treating a number of conditions, like anxiety, insomnia, and pain. But most of these claims don’t yet have strong evidence to support them, and more research is needed, although CBD has been found to be a viable treatment for at least some types of epilepsy. REFERENCES: Laprairie RB, Bagher AM, Kelly ME, Denovan-Wright EM. Cannabidiol is a negative allosteric modulator of the cannabinoid CB1 receptor. Br J Pharmacol. 2015;172(20):4790-4805. doi:10.1111/bph.13250 McPartland JM, Duncan M, Di Marzo V, Pertwee RG. Are cannabidiol and Δ(9) -tetrahydrocannabivarin negative modulators of the endocannabinoid system? A systematic review. Br J Pharmacol. 2015;172(3):737-753. doi:10.1111/bph.12944 Pisanti S, Malfitano AM, Ciaglia E, et al. Cannabidiol: State of the art and new challenges for therapeutic applications. Pharmacol Ther. 2017;175:133-150. doi:10.1016/j.pharmthera.2017.02.041 World Health Organization (WHO). Cannabidiol (CBD): Pre-Review Report. November 2017. Accessed June 28, 2020. https://www.who.int/medicines/access/controlled-substances/5.2_CBD.pdf Special thanks to Srikar Gade for help with fact-checking this video.
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Coming up at 4 PM Eastern time today on our podcast, hosts Shadd Dales and Anthony Varrell will be joined by Big Mike from Advanced Nutrients to discuss the importance of rescheduling cannabis in the US and EU markets. They'll discuss the global impact of rescheduling and the differences in cultivation and technology between the US and Europe. Big Mike will share that Advanced Nutrients' sales are up 40-46% from last February, having already broken their first-quarter sales from the previous year. The discussion will cover the importance of quality over quantity in the cannabis industry, with a focus on premium cultivation and bonus plans for cultivators. They'll also talk about the concept of trust in the cannabis industry, comparing the regulated market to the illicit market. The quality of cannabis in the EU versus California will be examined, with insights into how some EU countries are still learning, while exceptions like Portugal are growing high-quality cannabis. The conversation will also touch on California being the largest exporter of cannabis to Europe, exporting 15 million pounds annually. Finally, they'll discuss the potential global implications of rescheduling cannabis in the US. 0:00:00 - Introduction and Rescheduling Discussion 0:01:01 - Advanced Nutrients Sales Performance 0:02:47 - Cultivation Quality and Grower Incentives 0:04:42 - Comparing Cannabis Cultivation: California vs EU 0:07:09 - Global Cannabis Export Potential 0:10:59 - AI and Technology in Cannabis Cultivation 0:15:22 - US Research Opportunities in Cannabis 0:21:57 - Automation and AI in Cannabis Production 0:29:52 - Mary Jane Berlin Cannabis Conference Insights See you all at 4pm est and leave your comments! #CannabisRescheduling #CannabisIndustry #GlobalImpact #CannabisCultivation #AdvancedNutrients #PremiumCultivation #CannabisTrust #CannabisExport #CannabisPolicy Want to see last week's recap? https://youtu.be/Uq9fCsDTNhI Want to see more Cannabis Reform videos? https://youtu.be/NZDixPfHwe4 https://youtu.be/lIJzIa65ITA https://youtu.be/eaGMK1Va8cU https://youtu.be/vv8_HrxZNnw Want to be updated on Cannabis, Small Cap, AI, and Crypto? Subscribe to our Daily Baked in Newsletter! https://newsletter.thedalesreport.com/subscribe Find us as well on Facebook, Twitter, Instagram, LinkedIn and on the Web: Facebook: https://www.facebook.com/TheDalesReport Twitter: https://twitter.com/TheDalesReport Instagram: https://www.instagram.com/dalesreport LinkedIn: https://www.linkedin.com/company/the-dales-report/ Apple Podcasts: https://tinyurl.com/TDRTradetoBlackonApplePodcasts Spotify: https://tinyurl.com/TDRTradeToBlackonSpotify Website: https://thedalesreport.com/ For copyright matters, please get in touch with us at: [email protected] All views on the Trade To Black podcast and the guests on this podcast are purely opinions. You should not treat any opinions expressed by us or our guests as investment advice. The views on this podcast are solely intended to be informational and are not investment advice. Please go to our website for a full list of disclosures and details of any client relationship we have. https://thedalesreport.com/website-terms-of-use/
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