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In this conversation, Dr. Riley Kirk and Dr. Josh Kaplan delve into the complexities of cannabis research, particularly focusing on CBD and its therapeutic potential for conditions like epilepsy. Dr. Kaplan shares his journey into cannabis research, highlighting the significance of understanding CBD's mechanisms, the role of GPR55 in seizure management, and the challenges of dosing CBD effectively. They also discuss the entourage effect, the importance of personalized medicine, and the ongoing research into terpenes and their interactions with cannabinoids. The conversation emphasizes the need for further exploration in cannabis research to develop safe and effective therapies, especially for vulnerable populations like children. In this conversation, Josh Kaplan discusses the therapeutic potential of CBD, particularly in relation to traumatic brain injuries and neurodegenerative diseases. He emphasizes the safety of CBD compared to THC and explores its role in preventative treatments. The conversation also delves into ongoing clinical trials, particularly within the NFL, and the challenges faced in cannabis research, including dosing and the variability of individual responses to cannabinoids. Kaplan highlights the importance of understanding the entourage effect and the need for more personalized approaches in cannabis treatment. More about Dr. Kaplan: Dr. Kaplan is an Associate Professor in the Behavioral Neuroscience Program. His expertise is in neurophysiology, neuropharmacology, and animal behavior techniques, which his lab uses to study the therapeutic benefits and developmental consequences of cannabis in pre-clinical rodent models. His research seeks to optimize cannabinoid and terpene compositions to maximize benefit and minimize adverse consequences. Dr. Kaplan has a strong passion for teaching and communicating science. His scientific writing specializes in the science of cannabis and its medicinal utility. He was included in High Times' 100 Most Influential People in Cannabis (2018) and Cannabis Newsletter's Top 100 (2021). Follow Dr.Kaplan’s research: https://wp.wwu.edu/kaplanlab/ Preorder my book Reefer Wellness! https://www.amazon.com/Reefer-Wellness-Understanding-Cannabis-Medicine/dp/0593847156 Seed Giveaway Thank you to Royal Queen Seeds and Last Green Valley Seeds for donating to this week's giveaway! To enter, fill out the form below, winners will be selected at random. https://forms.gle/1vWtsBMGaux9x5Mf6 ✨ Want Exclusive Content? Join the Bioactive Patreon community for as little as $1/month to ask guests your burning questions, access exclusive content, and connect with Dr. Kirk one-on-one. www.Patreon.com/Cannabichem 🔔 Don’t forget to like, subscribe, and hit the notification bell for more expert insights into cannabis science, plant biology, and more! Keep up with Dr. Riley Kirk: https://www.bioactivepodcast.com/ https://www.youtube.com/@cannabichem https://instagram.com/cannabichem https://www.appliedpharmacognosy.org/ Timestamps: 00:00 Introduction to Cannabis Research and Its Importance 03:04 The Journey into CBD and Epilepsy 06:00 Understanding CBD's Mechanism of Action 08:54 The Role of GPR55 in Seizure Management 12:00 Exploring the Entourage Effect 14:53 Challenges in Dosing CBD for Multiple Conditions 18:02 Personalized Medicine and Endocannabinoid System 21:01 Researching Terpenes and Their Effects 24:01 Future Directions in Cannabis Research 34:12 The Therapeutic Potential of CBD 36:34 Traumatic Brain Injury and CBD Research 39:34 Clinical Trials and NFL Studies 48:01 Challenges in Cannabis Research 54:27 Dosing and Efficacy of CBD 01:00:24 The Entourage Effect and Individual Variability

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I review the legal form of THC called Delta-10! Delta-10 THC is one of the hundreds of cannabinoids you can find in hemp and cannabis. ► INSTAGRAM: @lowkey_fish ◄ https://instagram.com/lowkey_fish ► TWITTER: @lowkey_fish ◄ https://twitter.com/lowkey_fish ╔═╦╗╔╦╗╔═╦═╦╦╦╦╗╔═╗ ║╚╣║║║╚╣╚╣╔╣╔╣║╚╣═╣ ╠╗║╚╝║║╠╗║╚╣║║║║║═╣ ╚═╩══╩═╩═╩═╩╝╚╩═╩═╝ MORE LEGAL CANNABINOIDS REVIEWS: . 𝗧𝗛𝗖-𝗩: https://youtu.be/aHLKQIqwx3Y . 𝗗𝗘𝗟𝗧𝗔 𝟲𝗮𝟭𝟬𝗮: https://youtu.be/RzDE5tT1WgQ . 𝗛𝗛𝗖: https://youtu.be/gClrUPBAL7o . 𝗧𝗛𝗖-𝗢: https://youtu.be/VCRx8By2o80 . 𝗖𝗕𝗗: https://youtu.be/4-cc6WF0JCU . Chapters: 0:00 - What is Delta 10? 1:47 - Smoke Review Copyright ©️ 2022 Lowkey Fish. All rights reserved. __________________________________________________________________________________________ This video articulates the gist of the following: WHAT IS DELTA-10-THC? Delta-10 THC is one of the hundreds of cannabinoids you can find in hemp and cannabis. Unlike Delta-9 however, Delta-10 appears in such trace amounts that you’d waste an exhaustive amount of time and plant material trying to extract it from natural strains. In fact, Delta-10 is so elusive, laboratories often misidentify the compound for CBC or CBL using standard High Performance Liquid Chromatography methods, according to Extraction Magazine. HOW DOES DELTA-10-THC AFFECT THE BODY? While very little research has been done on its mechanism of action in the body, Delta-10 THC likely interacts with the endocannabinoid system in a similar way as other THC compounds. Delta-9 THC and Delta-8 THC have binding affinities towards CB1 receptors in the brain and nervous system, which produce varying levels of psychotropic effects. Delta-10 may interact similarly with CB1 receptors at high concentrations. CAN DELTA-10-THC GET YOU HIGH LIKE DELTA-8 OR DELTA-9 THC? According to Delta-10 can get you high. But not exactly like Delta-8 or Delta-9. Delta-9 has the most intense effect on a person’s pleasure, thought process, memory, coordination and perceptions. Delta-8 has a much lower potency in comparison and users report experiencing mild levels of appetite stimulation, and relaxation. Delta-10 is uplifting and perfect for daytime use said David. Delta-10 THC will appear in a urinalysis and may not be discernible from Delta-9. Long story short, better to be safe on this one. . #Delta10 #Legal #THC #D10 #Delta10thc #legalhigh #Cannabis #legalweed #delta8 . ⚠⚠**DISCLAIMER / WARNING**⚠⚠ No illicit substances were used in this video! This video is for informational and educational purposes only; do not try this substance or any other substance, whether it be legal or not. This video has been created strictly for education and harm reduction; to help people remain safe by properly educating them about the dangers & truths in an entertaining & artistic way. The information in this video is not intended or implied to be a substitute for professional medical advice, diagnosis or treatment. All content, including text, graphics, images, and information contained in this video is for general information & entertainment purposes only and does not replace a consultation with your own doctor/mental health professional. By viewing this video, you agree to never recreate anything discussed whatsoever. Do not replicate anything you see or hear in this video (or any other videos posted to this channel). This video/channel does not condone or glorify the usage of drugs. Thank you & stay safe :) . Find me literally anywhere on the internet! Here is ALL of my links: https://linktr.ee/lowkeyfish

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