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Delta-8 THC - is it legal? The DEA Interim Final Rules for enforcing the 2018 Farm Bill - which legalized hemp - may end up in all hemp farmers and processors being arrested for marijuana. New DEA Hemp Rules Spell Doom for CBD Industry - Delta-8 THC News Read more about the DEA Interim Final Rule by searching “DEA Hemp Rule” on our website "Cannabis Industry Lawyer"! Shout out to Rod Kight!! The DEA Rules for the 2018 Farm Bill are terrible & under a public comment period. This interim final rule amends the definition of marihuana extract to conform to the revised definitions of marihuana and tetrahydrocannabinols. This revised definition now includes the 0.3%-THC content limit for the extract, meaning hemp-derived extracts containing less than 0.3%-THC content are also decontrolled along with the plant itself. ______________________________________________ Footnotes (Headlines to Google): DEA JUST DROPPED A BOMB ON THE HEMP INDUSTRY. PART 1: HEMP EXTRACT (Cannabis Business Law - Kight On Cannabis) DEA JUST DROPPED A BOMB ON THE HEMP INDUSTRY. PART 2: DELTA-8 THC (Cannabis Business Law - Kight On Cannabis) ______________________________________________ *Update* If you’re reading this after October 9, 2020, unfortunately, we had to delete all links to outside sources. While Cannabis Legalization News is an educational news show, the very center of many of our discussions is cannabis. Cannabis currently remains federally illegal and YouTube is mandated by federal regulations. We implore you to go to our website “Cannabis Industry Lawyer” and subscribe to our newsletter so you can keep up with all cannabis legalization news. Please always comply with your jurisdiction’s cannabis laws. If they delete our channel, we’re sorry - we tried to comply but they said we did not.
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Parkinson’s disease, also known as PD, is the second most common neurodegenerative disorder. The disease is characterized by a loss of dopamine-producing neurons in the substantia nigra, which is an area of the brain responsible for movement. Cannabis, specifically CBD, has shown promise in treating some of the symptoms of PD. In this video we will define Parkinson’s disease and cannabis, explain how cannabis can help with PD, and physician perspectives on prescribing cannabis. This video was created by Demystifying Medicine students Simran Matharu, Mahek Minhas and Micaela McNulty in collaboration with the McMaster Demystifying Medicine Program Copyright McMaster University 2021 For more information visit: https://www150.statcan.gc.ca/n1/pub/82-003-x/2014011/article/14112-eng.htm Time Stamps: Introduction/What is Parkinson’s Disease? → 00:00 - 01:23 What is Cannabis? → 01:24 - 02:34 How Can Cannabis Help With Parkinson’s? → 02:35 - 05:09 Physician Perspectives → 05:10 - 07:19 Conclusion → 07:20 - 07:52 References: Bega, D., Simuni, T., Okun, M. S., Chen, X., & Schmidt, P. (2016). Medicinal cannabis for Parkinson's disease: Practices, beliefs, and attitudes among providers at national Parkinson Foundation centers of excellence. Movement Disorders Clinical Practice, 4(1), 90-95. Benner, E. J., Banerjee, R., Reynolds, A. D., Sherman, S., Pisarev, V. M., Tsiperson, V., Nemachek, C., Ciborowski, P., Przedborski, S., Mosley, R. L., & Gendelman, H. E. (2008). Nitrated alpha-synuclein immunity accelerates degeneration of nigral dopaminergic neurons. PloS one, 3(1), e1376. Clapper, J. R., Mangieri, R. A., & Piomelli, D. (2009). The endocannabinoid system as a target for the treatment of cannabis dependence. Neuropharmacology, 56, 235–243. de Lau, L. M., & Breteler, M. M. (2006). Epidemiology of Parkinson’s disease. The Lancet Neurology, 5(6), 525–535. Edelstein, O. E., Wacht, O., Isralowitz, R., Reznik, A., & Bachner, Y. G. (2020). Beliefs and attitudes of graduate gerontology students about medical marijuana use for Alzheimer’s and Parkinson’s disease. Complementary Therapies in Medicine, 52, 102418. Gardiner, K. M., Singleton, J. A., Sheridan, J., Kyle, G. J., & Nissen, L. M. (2019). Health professional beliefs, knowledge, and concerns surrounding medicinal cannabis – A systematic review. PLOS ONE, 14(5), e0216556. Hauser, R. A., Rascol, O., Korczyn, A. D., Jon Stoessl, A., Watts, R. L., Poewe, W., De Deyn, P. P., & Lang, A. E. (2007). Ten-year follow-up of Parkinson's disease patients randomized to initial therapy with ropinirole or levodopa. Movement disorders: official journal of the Movement Disorder Society, 22(16), 2409–2417. Jankovic, J. (2008). Parkinson’s disease: Clinical features and diagnosis. Journal of Neurology, Neurosurgery & Psychiatry, 79(4), 368–376. Klein, C., Karanges, E., Spiro, A., Wong, A., Spencer, J., Huynh, T., Gunasekaran, N., Karl, T., Long, L. E., Huang, X.-F., Liu, K., Arnold, J. C., & McGregor, I. S. (2011). Cannabidiol potentiates Δ9-tetrahydrocannabinol (THC) behavioural effects and alters THC pharmacokinetics during acute and chronic treatment in adolescent rats. Psychopharmacology, 218(2), 443–457. Lang, A. E., & Lozano, A. M. (1998). Parkinson’s Disease. New England Journal of Medicine, 339(16), 1130–1143. Laun, A. S., & Song, Z. H. (2017). GPR3 and GPR6, novel molecular targets for cannabidiol. Biochemical and biophysical research communications, 490(1), 17–21. Marras, C., Beck, J. C., Bower, J. H., Roberts, E., Ritz, B., Ross, G. W., Abbott, R. D., Savica, R., Van Den Eeden, S. K., Willis, A. W., & Tanner, C. (2018). Prevalence of Parkinson’s disease across North America. Npj Parkinson’s Disease, 4(1), 21. Nutt J. G. (2000). Response to L-dopa in PD: the long and the short of it. Neurology, 54(10), 1884–1885. https://doi.org/10.1212/wnl.54.10.1884 Oeckl, P., Hengerer, B., & Ferger, B. (2014). G-protein coupled receptor 6 deficiency alters striatal dopamine and cAMP concentrations and reduces dyskinesia in a mouse model of Parkinson's disease. Experimental neurology, 257, 1–9. https://doi.org/10.1016/j.expneurol.2014.04.010 Severe Spasticity. (2020). https://lioresal.com/severe-spasticity/. Venderová, K., Růzicka, E., Vorísek, V., & Visnovský, P. (2004). Survey on cannabis use in Parkinson's disease: subjective improvement of motor symptoms. Movement disorders: official journal of the Movement Disorder Society, 19(9), 1102–1106. https://doi.org/10.1002/mds.20111 Wang, M., Wang, Y.-H., Avula, B., Radwan, M. M., Wanas, A. S., Mehmedic, Z., van Antwerp, J., ElSohly, M. A., & Khan, I. A. (2017). Quantitative Determination of Cannabinoids in Cannabis and Cannabis Products Using Ultra-High-Performance Supercritical Fluid Chromatography and Diode Array/Mass Spectrometric Detection. Journal of Forensic Sciences, 62(3), 602–611. https://doi.org/10.1111/1556-4029.13341
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