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Delta 8 THC Compared to Delta 9 THC Professor DeBacco Delta-9 THC Explained As an activator of the CB1 receptor, delta-9-tetrahydrocannabinol — commonly known as THC is the main intoxicating component of cannabis. THC intoxication has been shown to increase blood flow to the prefrontal cortex, the region of the brain responsible for decision-making, attention, motor skills, and other executive functions. When THC binds to CB1 receptors in the brain's reward system, it can trigger feelings of euphoria. Much of THC's ability to relieve pain is due to its interaction with CB1 receptors in the midbrain. Delta-8 THC Explained Delta-8-THC is an isomer of Delta-9 THC It only differs from delta-9-THC by the placement of one atomic double bond. Generally, this chemical is produced in a lab, not extracted directly from the plant. It is actually synthesized from CBD Isolate. This creates a legal loophole, because the product is being sold as “hemp derived” even though it is actually a chemically produced THC isomer. Extraction Difference Delta 9 THC is a major cannabinoid that can be found in abundance and is easily extracted from in cannabis. Extracting Delta 8 THC is more challenging because it is a minor cannabinoid Synthesizing Delta 8 from CBD Delta 8 can be synthesized entirely from CBD with the use of solvents. Deriving Delta 8 from hemp ensures the final product is under the 0.3% THC level to be federally legal. Steps to Synthesize D8 THC from CBD isolate Dissolve into non-polar solvent of choice. Common solvents include heptane. Add a Lewis acid, like alumina, p-toluenesulfonic, or hydrochloric. Maintain the mixture at a temperature of 100 degrees C while continually stirring for upwards of 18 hours. Once the chemical reaction is complete, and the upper phase is separated, wash and neutralize the solution with 5% NaHCO3 Test for purity and contaminants using HPLC, separate the converted mixture into its “many cannabinoid parts”. Conversion is never 100% Different Effects Delta 9 is considerably more potent effects than Delta 8. Ex. paranoid delusions, mental fog, impaired motor skills, and increased feelings of anxiety. Delta 8 is reported to provide a more muted experience with most users feel a great sense of calm and clarity. However, many have reported a definite “high” to the experience, but not enough to impair the ability to form coherent thoughts or focus on activities. Onset Time Difference Delta 9 has an onset that is more rapid and instantaneous Delta 8 works slowly and gradually as it eases users into a more mellow state Similar End Products Both can be smoked as a flower, inhaled through vaping, consumed in edible form also with a wide variety of topicals, capsules, tinctures, edibles and other products. Legality Delta 9 THC in any amount over 0.3% is not legal at a federal level. State level depends entirely on their local laws. Delta 8 is still technically legal on a federal level. That's because of the ambiguities of the 2018 Farm Bill, which legalized hemp production. There is nothing within the bill that prohibits deriving Delta 8 from hemp and creating products with the compound. Hazy Area The psychoactive nature of Delta 8 has prompted a fair number of bans at the state level, though. Currently there are 15 states that restrict the sale and use of Delta 8 products, with another 6 states where legal action is pending. So while Delta 8 is more widespread at the moment than Delta 9, how long that will last has yet to be determined. Availability Delta 8 since it is federally legal can be shipped across state lines, unlike Delta 9. There are a lot more online retailers for Delta 8 products as a result. Remember: Delta 8 products are not regulated by the FDA, so it is up to you to seek out lab results tested from a third party lab. Delta 9 vs Delta 8 Delta 9 might be considered the “classic” choice by some within the cannabis community, Delta 8 has been quickly gaining in popularity due to its milder effects and legal availability. Since this is an isomer of Delta 9 it is also likely to come under some form of regulation in the future even though that may not currently be the case. Link to Lecture Slides: https://drive.google.com/file/d/1bTA2zy0R_dAN7zVTCzp0_XImiOmyHGlx/view?usp=sharing *Due to the description character limit the full work cited for "Delta 8 THC Compared to Delta 9 THC" can be viewed at... https://drive.google.com/file/d/1ET_IIIsXWyUZ_FuID5oXLumMOchlYSzr/view?usp=sharing
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Nextleaf Solutions CEO Paul Pedersen joined Steve Darling from Proactive to share news the company has been working in its Specialty Molecules division, to modify Delta-9-THC into a prodrug version of THC-O-Acetate commonly referred to as THC-O. Pedersen telling Proactive the company feels THC-O will not be subject to excise tax as it does not meet the definition of “Total THC” as defined under the Excise Act 2001. Pedersen also stated they are working right now to get products on the shelves by the end of the year.
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CBD Oil for Pancreatitis in Dogs – How Cannabis Hemp Tincture Can Help How Can CBD Oil Be Useful For Pancreatitis In Dogs? CBD oil is basically an extract from the cannabis or marijuana plant. Although it is extracted from the cannabis plant, it does not have any psychoactive properties like THC. It is also non-toxic and does not come with any side effects. According to several tests and studies, CBD is said to have certain useful properties that can work like a charm for both humans and dogs. These include anti-inflammatory, anti-anxiety, and pain-relieving properties. What Is Pancreatitis? It is sad to say that pancreatitis is one of those health conditions in dogs that can become fatal with time. It basically happens due to inflammation of the pancreas. Amongst the various organs inside the body, the pancreas is one of the important ones located on the right side of the abdomen. It is responsible for producing adrenaline and other useful enzymes that the body uses in order to digest food. Once the pancreas gets inflamed, the digestive enzymes tend to escape to the abdominal cavity that eventually leads to large scale damages to the intestines, liver and the pancreas. There are also situations wherein pancreatitis may happen without any prior notice. Symptoms of Pancreatitis There are several symptoms of pancreatitis. It is good to know that this disease may occur in a mild form or a serious form. Some of the major and common symptoms of pancreatitis are diarrhea, vomiting, abdominal pain, swollen abdomen, lethargy, loss of appetite, extreme weakness, and distended or bloating stomach. CBD Oil Is Rather Helpful In Pancreatitis When it comes to safe and natural options to help your dog with pancreatitis, one of the best examples is CBD oil. It is free from any psychoactive properties and side effects and it is also natural and safe. The anti-inflammatory and pain relieving properties of CBD oil can prove to be a boon when it comes to solving health problems such as pancreatitis. Subscribe: https://www.youtube.com/channel/UCLTYWIW3RAALS6EKGFRPIuw Connect with us on Facebook: https://www.facebook.com/Simply-Pets-Site-734737983533572/ Connect with us on Instagram & Pinterest: https://www.instagram.com/simplypetspage/ https://www.pinterest.com/petssimply/ Link to the Full Article: https://www.simplypets.com/cbd-oil-for-pancreatitis-in-dogs/ Connect with us at our website: https://www.simplypets.com/
