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Dr Sarah Barenbaum discusses alternatives to GLP-1 medications for weight loss. https://www.medscape.com/viewarticle/alternatives-glp-1-medications-weight-loss-2025a10007f9?src=soc_yt -- TRANSCRIPT -- Hi. My name is Dr Sarah Barenbaum. Today, I’m going to be talking about alternative weight loss medications other than glucagon-like peptide 1 (GLP-1) receptor agonists. Losing weight and maintaining weight loss are really hard because of biological forces that limit weight loss and promote weight regain over time. Fortunately, for those who qualify, we have FDA-approved medications that can help individuals lose and maintain weight loss. There’s been a large amount of hype more recently about our incretin agonists, often called the GLP-1 receptor agonists, semaglutide and tirzepatide. But these medications are not magic bullets by any means, and they have several limitations. For example, some people do not lose weight with them, or some people cannot tolerate them. And many people don’t have access to them, either due to shortages or restricted insurance coverage and high out-of-pocket costs. This is why it’s important to know there are five other medications that are FDA approved for weight management. These medications are phentermine; orlistat; a combination pill of phentermine and topiramate; a combination pill of bupropion and naltrexone; and liraglutide, which is actually a once-daily GLP-1 receptor agonist. Phentermine is only approved for short-term use or 3-month use. The rest are all approved for long-term use for chronic weight management. If your patient is unable to take a GLP-1 for whatever reason, or if [GLP-1s] are ineffective, consider using one of these other medications, which can also be highly effective in helping patients lose and maintain weight loss. Transcript in its entirety can be found by clicking here: https://www.medscape.com/viewarticle/alternatives-glp-1-medications-weight-loss-2025a10007f9?src=soc_yt
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Serotonin Centers Semaglutide Weight Loss Treatment has gained significant attention in recent years as a potential solution for individuals struggling with obesity. Semaglutide, a medication originally used for managing type 2 diabetes, has shown promising results in promoting weight loss when used at higher doses. The treatment works by targeting specific receptors in the brain that control appetite and food intake, leading to reduced caloric intake and ultimately weight loss.
How does Semaglutide work?
Semaglutide is a glucagon-like peptide-1 (GLP-1) receptor agonist, which means it mimics the action of a natural hormone in the body that helps regulate blood sugar levels and appetite. When Semaglutide is administered at higher doses than those typically used for diabetes management, it interacts with serotonin receptors in the brain that are involved in controlling food intake. By increasing feelings of fullness and reducing cravings, Semaglutide can help individuals eat less and lose weight.
In addition to its effects on appetite, Semaglutide also has metabolic benefits that can contribute to weight loss. It helps regulate glucose metabolism, improves insulin sensitivity, and promotes fat loss, all of which are beneficial for individuals looking to shed excess pounds.
Overall, Semaglutide offers a comprehensive approach to weight loss by addressing both the physiological and psychological factors that contribute to obesity. By targeting specific neurotransmitters in the brain, it can help individuals make healthier food choices, reduce portion sizes, and ultimately achieve their weight loss goals.
What to expect during Semaglutide treatment?
Before starting Semaglutide treatment, individuals will undergo a thorough evaluation to determine if they are good candidates for the medication. This may include blood tests, medical history review, and assessment of weight-related health issues. Once cleared for treatment, patients will receive instructions on how to administer Semaglutide, typically through self-injection once a week.
During the initial weeks of treatment, individuals may experience mild side effects such as nausea, vomiting, or diarrhea. These symptoms usually subside as the body adjusts to the medication. It is essential to follow the prescribed dosage and consult with healthcare providers if side effects persist or worsen.
With continued use of Semaglutide, individuals can expect to see gradual but steady weight loss over time. The timeline for weight loss may vary depending on factors such as starting weight, diet, exercise habits, and overall health. Healthcare providers will monitor progress and make adjustments to the treatment plan as needed to ensure optimal results.
Benefits of Semaglutide for weight loss
One of the key advantages of Semaglutide for weight loss is its effectiveness in helping individuals achieve significant and sustainable results. Studies have shown that when used in conjunction with a healthy diet and exercise, Semaglutide can lead to greater weight loss compared to lifestyle interventions alone. The medication can also help improve metabolic health markers such as blood sugar levels, cholesterol, and blood pressure.
In addition to its weight loss benefits, Semaglutide may also have positive effects on overall well-being and quality of life. By helping individuals regain control over their eating habits and body weight, Semaglutide can boost confidence, energy levels, and self-esteem. This holistic approach to weight management sets Semaglutide apart as a promising option for individuals struggling with obesity.
Furthermore, Semaglutide has been shown to have lasting effects on weight maintenance, making it a valuable tool for long-term success. By resetting appetite signals in the brain and promoting sustainable lifestyle changes, Semaglutide can help individuals not only lose weight but also keep it off in the months and years to come.
