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Click Here to Subscribe: http://Bit.ly/ThomasVid Website: http://ThomasDeLauer.com Get the Apparel I Wear at http://Hylete.com Ketogenic Diet vs. Kidneys | Keto’s Effect on the Kidneys | Kidneys Stones Explained- Thomas DeLauer… Keto & Gene Expression: A study published in the journal Kidney International looked at nephropathy (term used when the kidneys start to incur damage, which can ultimately lead to kidney failure) in diabetic mice (3) The researchers found the genes responsible for nephropathy (nephrin, ZO-1 and podocin) were reversed - this helped restore the mice’s kidneys back to healthy functioning. Specifically, the study found that keto increased the expression of SIRT1, which led to a reduction in the genes responsible for nephropathy. In indications of energy surplus, such as glycogen and insulin, inhibit activation of AMPK - ketosis decreases these factors that inhibit AMPK. Through a very long process ketosis is able to activate SIRT1 indirectly through activation of AMPK. https://www.asn-online.org/education/kidneyweek/2017/program-abstract.aspx?controlId=2781128 SIRT1: SIRT1 is a protein or vehicle that requires NAD+ to function - SIRT1 takes acetyl groups off of proteins. SIRT enzymes “turn off” certain genes that promote aging, such as those involved in inflammation, in fat synthesis and storage, and in blood sugar management. When proteins are undergoing stress, acetyl groups are added to proteins as a response to changes induced by inflammation and oxidation. Sirtuins (like SIRT1) remove these acetyl groups to keep the protein in service longer than usual, while simultaneously stabilizing the charge state of the carbon backbone in protein to resist any further changes in their shape. This allows your cellular proteins to live longer and you can save energy on other processes. Keto & Glomerular Lesions: Glomerular filtration rate (GFR) is a test to measure how well the kidneys filter blood and remove waste. Glomeruli, the small units within the kidney where blood is filtered - they act as tiny filters within the kidneys and each kidney contains millions of glomeruli. If the glomeruli become damaged, the kidney can no longer remove waste and excess fluids efficiently - blood and protein cannot be filtered and are excreted in the urine. Too much glucose may cause glomerular lesions in patients with poor glucose control, leading to impairment of the kidneys. Glomerulonephritis, a group of diseases that cause inflammation and damage to the kidney's filtering units - glomerulonephritis refers to a range of inflammatory kidney conditions of the tiny blood vessels in the kidneys. High glucose levels are thought to make the blood flow into the kidney at a higher speed, putting a strain on the filtering process and raising blood pressure. The capillaries in the glomerulus collapse and can leave the glomeruli with scarring. Meta Analysis - British Journal of Nutrition: The review measured the impact of low carb diet on renal function taking into account 1000 people from nine randomised controlled trials found that: “a low carbohydrate diet and the corresponding high-protein diet was not harmful for renal function in overweight and obese individuals without renal dysfunction.” Furthermore, it concluded that a low carb diet may even improve renal function thanks to its weight loss effects. References: 1) Impact of low-carbohydrate diet on renal function: a meta-analysis of over 1000 individuals from nine randomised controlled trials. (2016, August 28). Retrieved from https://www.cambridge.org/core/journals/british-journal-of-nutrition/article/impact-of-lowcarbohydrate-diet-on-renal-function-a-metaanalysis-of-over-1000-individuals-from-nine-randomised-controlled-trials/0EAA25E700C06D2C5125F0AB195FB33F 2) University of Wisconsin Hospitals and Clinics Authority. (2010, June 24). How Do Kidney Stones Form? Retrieved from https://www.uwhealth.org/urology/how-do-kidney-stones-form/11210 3) Nesbitt, H. (n.d.). Kidney Week. Retrieved from https://www.asn-online.org/education/kidneyweek/2017/program-abstract.aspx?controlId=2781128 4) Hong Q , et al. (n.d.). Increased podocyte Sirtuin-1 function attenuates diabetic kidney injury. - PubMed - NCBI. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/29477240 5) Nutritional Ketosis and Mitohormesis: Potential Implications for Mitochondrial Function and Human Health. (2018, February 11). Retrieved from https://www.hindawi.com/journals/jnme/2018/5157645/

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Join our newsletter & Get our new FREE 5-Day Nutrition Course: https://www.bodyweightmuscle.com/weightlossonutopilot/ Interested in personal coaching? Fill in the following form: https://www.bodyweightmuscle.com/dadbod/ Read my latest best-selling book ⤵️ The 7AM Workout Edge: https://www.amazon.com/M-Workout-Edge-Wake-Work/dp/1544541031/ Other books by me: https://www.amazon.com/stores/Anthony-Arvanitakis/author/B00LQED6CI Disclaimer: All information in this YouTube channel is presented with good intentions. You must always consult your physician before starting any exercise/diet program, especially if you have any medical condition or injury that contraindicates physical activity. All forms of exercise pose some inherent risks. You must take full responsibility for your safety and know your limits. Before practicing the exercises in this book, make sure that any kind of equipment or surface you train on is well maintained. Do not take risks beyond your level of experience, aptitude, training, and fitness. If you experience any acute or chronic pain, consult a physician. This publication is intended for informational use only and I will not assume any liability or be held responsible for any form of injury by the utilization of this information.

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When it comes to the health and wellness industry, there’s always a new trend or product that promises to help you reach your goals faster and easier. One of the latest buzzwords in the market is the combination of Keto and Apple Cider Vinegar (ACV) gummies. These tiny treats offer a dual benefit of promoting ketosis while also harnessing the power of ACV for added health benefits. If you’re curious about this unique combination and how it can benefit your health, keep reading to learn more.

The Power of Ketosis

Ketosis is a metabolic state in which your body burns fat for fuel instead of carbohydrates. This process can help you lose weight, increase energy levels, and improve mental clarity. By following a ketogenic diet, you can train your body to enter ketosis and reap the benefits of this fat-burning state.

When you limit your intake of carbs and consume a moderate amount of protein, your body will start producing ketones, which are used as fuel instead of glucose. This shift in fuel source can lead to rapid weight loss and improved overall health. Ketosis has also been shown to reduce inflammation, regulate blood sugar levels, and enhance cognitive function.

One of the challenges of following a ketogenic diet is sticking to the strict macronutrient ratios required to stay in ketosis. This is where Keto gummies can be a game-changer. These convenient and delicious treats provide a low-carb, high-fat option that can help you stay on track with your ketogenic goals, even when you’re on the go.

The Benefits of Apple Cider Vinegar

Apple cider vinegar has been used for centuries as a natural remedy for various health issues. It is packed with antioxidants and beneficial compounds that can improve digestion, promote weight loss, and boost overall health. ACV has been shown to help regulate blood sugar levels, lower cholesterol, and even improve skin health.

One of the key components of ACV is acetic acid, which has been linked to numerous health benefits. This powerful compound can help reduce inflammation, kill harmful bacteria, and aid in weight loss by promoting feelings of fullness and reducing cravings. By incorporating ACV into your daily routine, you can support your body’s natural detoxification processes and improve your overall well-being.

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While consuming straight apple cider vinegar can be harsh on your teeth and stomach lining, ACV gummies offer a tasty and convenient alternative. These gummies provide all the benefits of apple cider vinegar in a delicious and easy-to-take form, making it easier than ever to incorporate this powerful ingredient into your daily routine.

How Keto & ACV Gummies Work Together

By combining the benefits of ketosis and apple cider vinegar, Keto & ACV gummies offer a powerful tool for achieving your health and wellness goals. These gummies provide a convenient way to support your ketogenic lifestyle while also reaping the benefits of ACV. By incorporating these delicious treats into your daily routine, you can enjoy the best of both worlds and optimize your health from the inside out.

When you use Keto & ACV gummies, you are not only supporting your body’s natural fat-burning processes through ketosis but also harnessing the power of apple cider vinegar to boost your overall health. These gummies are specifically formulated to help you stay in ketosis while providing all the benefits of ACV, making them an ideal choice for anyone looking to enhance their health and well-being.

Whether you’re looking to lose weight, improve your energy levels, or simply support your overall health, Keto & ACV gummies can be a valuable addition to your daily routine. These delicious treats offer a convenient way to enjoy the benefits of ketosis and apple cider vinegar without any of the hassle or unpleasant taste. With Keto & ACV gummies, you can take your health to the next level and enjoy the dual benefits of these powerful ingredients.

FAQs about Keto & ACV Gummies

1. Can Keto & ACV gummies help me lose weight?

Yes, Keto & ACV gummies can support weight loss by promoting ketosis and providing the benefits of apple cider vinegar, such as improved digestion and increased feelings of fullness.

2. Are there any side effects of taking Keto & ACV gummies?

While Keto & ACV gummies are generally safe for most people, it’s always best to consult with a healthcare professional before adding any new supplement to your routine.

3. How often should I take Keto & ACV gummies?

The recommended dosage of Keto & ACV gummies may vary depending on the brand and formulation. Be sure to follow the instructions on the product label or consult with a healthcare provider for personalized guidance.

4. Can I take Keto & ACV gummies if I’m not following a ketogenic diet?

Yes, you can still enjoy the benefits of Keto & ACV gummies even if you’re not following a strict ketogenic diet. These gummies can support your overall health and well-being, regardless of your dietary preferences.

5. Where can I purchase Keto & ACV gummies?

Keto & ACV gummies can be found online or at select health food stores. Be sure to choose a reputable brand that uses high-quality ingredients to ensure the best results.

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Unwavering Commitment: The Love Story of Pierce Brosnan and Keely Shaye Smith

Pierce Brosnan, the renowned actor best known for his portrayal of James Bond, has had a significant impact on cinema over the years. However, the story of his life goes beyond the silver screen. Central to his journey is the love and devotion he shares with his wife, Keely Shaye Smith. Their relationship reflects a bond that transcends the typical narratives of celebrity romances, showcasing genuine affection, support, and the triumph of personal struggles. As they navigated the complexities of life in the limelight, their devotion served as an inspiring testament to love and resilience.

Keeley Shaye Smith, a talented actress, producer, and journalist, has always been more than just Brosnan’s partner. She has played a vital role in his life, offering support, encouragement, and understanding as they tackled various challenges together. Over the years, the couple has faced personal hurdles, notably Keely’s battle with weight. What thus becomes a central theme is a narrative of dedication not only in their romantic endeavors but also in their personal growth and health journeys. Their love and mutual respect allowed them to embrace change and embark on an inspiring journey towards health and wellness.

Keely’s remarkable journey of losing over 100 pounds serves as a compelling chapter in their story. Fueled by her commitment to health and her love for Brosnan, Keely has made significant strides in her wellness journey. Her determination not only transformed her physical appearance but also had a profound impact on her mental state, enabling her to reclaim her confidence and vitality. The support she received from Brosnan throughout this transformation exemplifies a partnership built on encouragement. As they moved through this transformative period together, they stood as a beacon of motivation for others grappling with similar challenges.

The Power of Support: How Love Fuels Transformation

In any relationship, the support partners provide one another can be the difference between success and failure in personal endeavors. Brosnan’s unwavering support for Keely during her transformative journey highlights how powerful love can be when it comes to achieving health goals. His presence as a constant motivator played a pivotal role in her decision to pursue a healthier lifestyle. Rather than merely offering words of encouragement, Brosnan engaged in activities that promoted fitness and well-being for both of them, making their relationship even stronger in the process.

A successful health transformation requires not just physical changes but also psychological adjustments. Brosnan understood that Keely’s journey was as much about her mental health as it was about losing weight. He encouraged her to embrace this journey with positivity and grace. By finding joy in physical activity together, such as hiking, biking, or simply engaging in nutritious meal planning, Brosnan helped Keely shift her mindset from one of limitation to one of empowerment. Their joint efforts created a nurturing environment that fostered growth and positivity.

Moreover, Brosnan’s role extended beyond just personal support; he often highlighted Keely’s journey publicly, advocating for self-love and acceptance. This level of visibility was immensely beneficial in combatting the often toxic standards of beauty portrayed by the media. Through his admiration for Keely, he showcased the reality that true beauty lies in resilience and authenticity. Their journey together evolved into a powerful narrative of love that inspires countless others, proving that with the right support, individuals can overcome obstacles and achieve their desired goals.

A Journey of Self-Discovery: Keely’s Path to Health

Keely Shaye Smith’s journey was not simply a matter of losing weight; it became a path to self-discovery. It involved understanding her body, recognizing her needs, and making conscious choices that aligned with her values and aspirations. This transformation required deep introspection, leading to valuable revelations about health, balance, and life priorities. The journey was not without its trials, but each hurdle helped her grow stronger and more self-aware.

Throughout this journey, Keely prioritized a holistic approach to health. By incorporating mindfulness practices, such as meditation and yoga, along with physical fitness and nutrition, she began to view her body in a new light. This multi-faceted approach allowed her to honor her body while striving for improvement. Each experience enriched her life, leading to immense growth and a renewed sense of purpose. This journey was one of reclaiming not just her physical health, but her mental and emotional well-being as well.

Keely’s story has resonated with many, as it reflects the struggles and victories that countless individuals face. The journey to weight loss can often feel isolating, but her openness about her experiences fosters a sense of community for others on similar paths. Keely doesn’t shy away from discussing her challenges, which serves not only to inspire but also to normalize these struggles. Her story is a reminder that everyone can embark on their journey of transformation fueled by self-love and the support of loved ones.

Celebrating Achievements: The Role of Transformation in a Relationship

The successful transformation that Keely has undergone has added a new dimension to the relationship she shares with Pierce Brosnan. Achievements, both individual and joint, serve as a cornerstone for a relationship, nurturing the bond between partners. As Keely embraced a healthier lifestyle, Brosnan celebrated these victories alongside her, creating shared experiences that deepened their connection. The journey led them to discover new ways of engaging and enjoying life together, ultimately enriching their lifelong partnership.

Moreover, the celebration of achievements extends beyond personal milestones. As a couple, they have embraced opportunities to promote health and wellness together, becoming advocates for a balanced lifestyle. Their shared passion for fitness and holistic well-being allows them to support one another in maintaining their health journeys. These mutual commitments have reinforced their partnership, creating a dynamic where each individual thrives while also uplifting the other.

Celebrating achievements as a couple strengthens the emotional bond and creates lasting memories. Brosnan and Keely have undoubtedly shared countless moments of joy throughout their transformations. From exploring new hobbies to engaging in wellness events, each experience has fostered a sense of teamwork and camaraderie, showcasing the beauty of their relationship. The celebration of each milestone together serves as a reminder that love, when rooted in support and understanding, can propel both partners toward achieving their dreams.

A Legacy of Inspiration: Motivating Others Through Their Journey

Pierce Brosnan and Keely Shaye Smith stand as paragons of inspiration, not just for their romantic involvement but for their commitment to personal growth and health. Their story has become a source of motivation for countless individuals grappling with self-image and health challenges. Through sharing their experiences and highlighting the power of love and dedication, they foster an environment that encourages others to pursue their wellness journeys unapologetically. Their visibility as a couple has opened dialogues around self-love, support, and personal triumph.

Keely’s transformation, especially, serves as a beacon of hope for women everywhere. By openly discussing her struggles, she demystifies the process of weight loss and wellness. This discourse encourages others to embrace their journeys with compassion and resilience. Brosnan’s steadfast support amplifies this message, highlighting that share responsibility for each other’s well-being makes profound impacts on relationships and individual journeys. The simplicity of love and encouragement can ignite profound change.

As they continue to pursue health and wellness while nurturing their partnership, Brosnan and Keely leave a lasting legacy of resilience. They remind us that while the road to transformation may be challenging, it can also be rewarding, especially when partners support each other wholeheartedly. Their journey will reverberate through time, inspiring those who witness their love story to embark on their paths toward healthier, happier lives.

A Comprehensive Reflection on Their Journey and Support

Reflecting upon the incredible journey of Pierce Brosnan and Keely Shaye Smith, numerous themes emerge. Central to their narrative is the unwavering love that has fueled both individual and collective growth. Their relationship illuminates a path for others seeking motivation and affirmation in their journeys, showing that love can be a powerful catalyst for transformation. The story encapsulates the importance of genuine support and self-compassion in fostering a happy and healthy life.

Furthermore, the significance of personal health resonates deeply within their tale. Keely’s remarkable weight loss achievement exemplifies how determination coupled with support can yield astounding results. Her transition emphasizes the connection between mental and physical health, as both aspects are critical for achieving overall wellness. This journey also encourages individuals to embrace their transformations wholeheartedly, recognizing that change can lead to empowerment and increased confidence.

In conclusion, the compelling narrative of Pierce Brosnan and Keely Shaye Smith encompasses love, support, and resilience. Their story transcends the challenges they’ve faced—showcasing how two individuals united in partnership can achieve remarkable transformations. For those looking to embark on their health journeys, their experiences serve as an inspiring reminder that with love and commitment, anything is possible. As they continue their journey together, Brosnan and Keely remain a testament to the enduring power of partnership and the possibility of personal transformation.

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