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There are numerous benefits to incorporating BioDetox Lean Keto ACV Gummies into your weight loss journey. Some of the key benefits include:
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Are there any side effects?
As with any supplement, it’s important to consult with your healthcare provider before adding BioDetox Lean Keto ACV Gummies to your routine. While these gummies are made with natural ingredients, some individuals may experience minor side effects such as digestive issues or allergic reactions.
If you experience any negative side effects while taking BioDetox Lean Keto ACV Gummies, discontinue use and consult with your healthcare provider immediately.
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If you’re looking for a natural, effective way to slim down and improve your overall health, BioDetox Lean Keto ACV Gummies are worth considering. With their powerful blend of apple cider vinegar and other key ingredients, these gummies can help you reach your weight loss goals safely and efficiently.
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Calling all those with a passion for cardiovascular prevention! In this episode of the CardioNerds Cardiovascular Prevention Series, we take a deep dive into the world of glucagon-like peptide-1 (GLP-1) receptor agonists. Along the way, you’ll hear about the biology of the GLP-1 molecule and its related peptides, learn more about how GLP-1 agonists promote glycemic control, weight loss, and cardiometabolic health, and explore the current body of literature supporting the individualized application of these medications to patients with diabetes, obesity, and/or ASCVD. Join Dr. Christian Faaborg-Andersen (CardioNerds Academy Fellow and Internal Medicine Resident at MGH), Dr. Gurleen Kaur (Director of the CardioNerds Internship, Chief of House Einthoven, and Internal Medicine resident at BWH), and Dr. Rick Ferraro (CardioNerds Academy House Faculty and Cardiology Fellow at JHH) for a wide-ranging discussion on GLP-1 and GIP agonists with Dr. Dennis Bruemmer (Cardiologist and Director of the Center for Cardiometabolic Health in the section of Preventive Cardiology at the Cleveland Clinic). Show notes were drafted by Dr. Christian Faaborg-Andersen. Audio editing was performed by CardioNerds Academy Intern, student Dr. Tina Reddy. This episode was produced in collaboration with the American Society of Preventive Cardiology (ASPC) with independent medical education grant support from Novo Nordisk. See below for continuing medical education credit. Claim CME for this episode HERE. CardioNerds Prevention PageCardioNerds Episode PageCardioNerds AcademyCardionerds Healy Honor Roll CardioNerds Journal ClubSubscribe to The Heartbeat Newsletter!Check out CardioNerds SWAG!Become a CardioNerds Patron! Pearls and Quotes - GLP-1 Agonists: Mechanisms to Applications The selection and dosing of GLP-1 and GIP agonists (GLP-1s and GIPs) depends on their intended use as an anti-glycemic or anti-obesity agent. The cardiovascular benefits of GLP-1s and GIPs may be independent of improvements in glycemic control, and in part be driven by reduction in inflammation, a key driver of arterial plaque formation. In patients with comorbid coronary artery disease, obesity, and diabetes, GLP-1 agonists and SGLT-2 inhibitors should be used as first-line agents, over metformin. Tirzepatide is a dual agonist that activates GIP and GLP-1 receptors. GIP is highly expressed in the brain, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Caution should be used with GLP-1 agonists in patients with long-standing diabetes complicated by gastroparesis, as well as incompletely treated diabetic retinopathy. GI upset is not uncommon with GLP-1/GIP agonists, and switching to a different agonist is unlikely to help. Show notes - GLP-1 Agonists: Mechanisms to Applications What are the mechanisms of action by which GLP-1 and GIP controls blood sugar and body weight? Glucagon-like peptide-1 (GLP-1) is an endogenous hormone that is secreted in response to an oral glucose load. It promotes insulin release, inhibits glucagon secretion, and slows gastric emptying via the brain-intestine axis, leading to satiety. GLP-1 agonists are medications that mimic the effect of this hormone and, on average, lower hemoglobin A1C by 0.8% to 1.5%. These medications include semaglutide, liraglutide, and dulaglutide. Glucose-dependent insulinotropic polypeptide (GIP) is also an endogenous hormone, similarly secreted by the body in response to an oral glucose load such as a meal. GIP is highly expressed in the arcuate nucleus and hypothalamus, which may mediate satiety, promote energy expenditure, and enhance peripheral glucose metabolism. Tirzepatide is a dual GLP-1/GIP agonist. What is the role of GLP-1/GIP agonists in patients with overweight/obesity and/or type 2 diabetes? How does the dosing of GLP-1/GIP medications change with their intended disease target?
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In this inspiring episode of The WeightCare Podcast, Sharon Polsky, your GLP-1 Fact Fairy, welcomes Jacqueline Serrao, a successful WeightCare customer. Jacqueline shares her compelling journey of weight loss, including how she managed to lose an impressive 57 pounds despite facing various challenges. Jacqueline, a 41-year-old lawyer from Long Beach, California, details her lifelong struggle with weight, influenced by genetics and lifestyle choices. From being an active child involved in sports to experiencing the "freshman 15" in college, Jacqueline’s weight fluctuated significantly over the years. She discusses how stress during law school and comfort eating in her relationship contributed to her weight gain, eventually hitting an all-time high of 297 pounds. Jacqueline's inspiring story highlights the role of GLP-1 weight loss medications in her transformation. She candidly talks about the lifestyle changes she made, such as focusing more on healthy choices without extreme dieting or daily gym visits. Sharon and Jacqueline emphasize the importance of open conversations about weight and the powerful mental and physical benefits of GLP-1 medications, beyond just weight loss. Learn about the impact of GLP-1s on reducing food-related anxiety and providing mental clarity. Jacqueline recounts how her relationship with food changed dramatically, allowing her to prioritize her health over constant food cravings. She also discusses side effects like nausea and constipation, which she found manageable and worth the trade-off for the immense benefits she gained. Listeners are encouraged to seek professional advice about GLP-1s and not be swayed by misinformation. Jacqueline’s story, filled with honest reflections and practical tips, aims to inspire and provide hope for anyone struggling with weight management. Key Moments 00:00 Eating treats yet losing weight is inspirational. 05:44 Weight gain began at age 19, ongoing. 06:34 Weight loss challenges: metabolism changes over time. 11:56 Prioritizing food over relationships until changes. 13:57 Lost desire to drink, feeling more settled. 16:14 Family using meds; thriving with healthier choices. 19:09 Consult professionals, not online anecdotes or research. Key Takeaways Transformation Beyond Physical Appearance: Jacqueline lost 57 pounds, but the most compelling part of her journey is the mental clarity and reduced anxiety she gained. Real-Life Experiences: She talks about dealing with stress eating, the yo-yo effect of weight gain and loss, and how her relationship with food changed since starting GLP-1 medications. The Impact of GLP-1 Medications: Jacqueline highlights how essential GLP-1 medications were in her journey—helping her feel less tethered to food, reducing her anxiety, and improving her sleep. Overcoming Side Effects: While experiencing some nausea and minor side effects initially, Jacqueline believes the benefits far outweigh them. De-Stigmatizing Conversations Around Weight and Medication: Both Jacqueline and Sharon emphasize the importance of normalizing conversations about weight and the use of GLP-1 medications. Think of our podcast as your personal toolbox, filled with the tools you need to build and maintain your health. Whether you're considering GLP-1 medications or looking for holistic weight management strategies, this podcast is designed to empower you with knowledge and support. Our panel of global experts will explore topics such as Obesity, PCOS, Metabolic Health, Liposuction and Bariatric Surgery, Exercise & Nutrition, Monitoring Your Progress, and more. We'll also hear from GLP-1 users who will share their experiences - the good, the bad, and the ugly - offering valuable insights to help you avoid common pitfalls. Our aim is to provide accurate information about GLP-1's to empower you in making informed decisions about your health. The WeightCare Podcast is for informational and educational purposes only. The content shared here represents the views and opinions of the host and guests and should not be considered medical, health, or professional advice. This podcast is not a substitute for individualized care from qualified medical providers. Please consult with your healthcare provider before making decisions that may affect your health and wellness. Any statements about treatments, health protocols, or medications discussed are based on personal experience or professional expertise and may not be suitable for everyone. Always seek personalized advice from a licensed healthcare professional who understands your specific health needs.
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