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This Harvard Medical School Continuing Education video examines these key questions: When should GLP-1 receptor agonists be used for weight loss and in what dosage? What cautions should physicians be aware of when prescribing GLP-1 RA? Dr. Lee-Shing Chang, MD, an endocrinologist at Brigham and Women’s Hospital in Boston, Massachusetts, reviews the medical indications and side effects of GLP-1 receptor agonists when used for weight loss. Dosing and administration are discussed and contraindications including pregnancy, retinopathy, and hypoglycemia are highlighted. 00:00 | Introduction 00:38 | Indications and contraindications for liragutide and semaglutide in weight loss 03:56 | Administration and dosing of GLP-1 receptor agonists 06:15 | Gastrointestinal side effects of GLP-1 receptor agonists 07:41 | Future directions for GLP-1 receptor agonists This video was peer reviewed by Dr. Jonathan Salik, TMD, MHPEd, Instructor of Medicine, Massachusetts General Hospital; and Dr. Sugantha Sundar, MD, Assistant Professor of Anesthesia, Beth Israel Deaconess Medical Center, to validate the quality and accuracy of the content. References: Muskiet MHA, Tonneijck L, Smits MM, et al. GLP-1 and the kidney: from physiology to pharmacology and outcomes in diabetes. Nat Rev Nephrol. 2017;13(10):605-628. doi:10.1038/nrneph.2017.123 Pi-Sunyer X, Astrup A, Fujioka K, et al. A Randomized, Controlled Trial of 3.0 mg of Liraglutide in Weight Management. N Engl J Med. 2015;373(1):11-22. doi:10.1056/NEJMoa1411892 Wilding JPH, Batterham RL, Calanna S, et al. Once-Weekly Semaglutide in Adults with Overweight or Obesity. N Engl J Med. 2021;384(11):989. doi:10.1056/NEJMoa2032183 Rubino DM, Greenway FL, Khalid U, et al. Effect of Weekly Subcutaneous Semaglutide vs Daily Liraglutide on Body Weight in Adults With Overweight or Obesity Without Diabetes: The STEP 8 Randomized Clinical Trial. JAMA. 2022;327(2):138-150. Rubino D, Abrahamsson N, Davies M, et al. Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity: The STEP 4 Randomized Clinical Trial. JAMA. 2021;325(14):1414-1425. doi:10.1001/jama.2021.3224 Notice: At this time, the content in this video is not accredited.
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Shedding a few pounds is never easy, but what if you could do it with the help of just one pill? Drug makers have big plans for Ozempic, the popular weight-loss GLP-1 agonist drug, now in pill form. Keep your eyes on YouTube to see just how revolutionary this breakthrough could be! Host: Dr. Dave Montgomery http://TheGoodDrDave.com --Instagram https://www.instagram.com/thegooddrda... --Twitter https://twitter.com/thegooddrdave --Facebook https://www.facebook.com/thegooddrdave The Good Doctor TV web series: (see all of Season 1) http://thegooddoctortv.com/?reqp=1&reqr YouTube Channels: https://www.youtube.com/c/TheGoodDrDave
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#shorts #motivation #wisdom #inspirational #hopecore #successquotes Fair Use Disclaimer This video is for educational and transformative purposes, falling under the Fair Use Doctrine (17 U.S.C. §107). It provides original commentary, critique, and a thoughtful revision, contributing added value beyond the original sources. Content Usage: If you are a copyright holder and believe your material has been used unfairly, please contact me at [ [email protected] ] I will address your concerns promptly and, if necessary, remove the content in question.
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