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The Science behind Marijuana (Cannabis), Marijuana mechanism of action. Source of information: National Institute on Drug Abuse; National Institutes of Health; U.S. Department of Health and Human Services. Purchase a license to download a non-watermarked version of this video on AlilaMedicalMedia(dot)com Check out our new Alila Academy - AlilaAcademy(dot)com - complete video courses with quizzes, PDFs, and downloadable images. Voice by: Sue Stern Animation ©Alila Medical Media. All rights reserved. Marijuana, also known as cannabis, among other names, is a preparation of the Cannabis sativa plant - the hemp plant, intended for recreational and medicinal uses. The main psychoactive chemical in marijuana is delta-9-tetrahydro-cannabinol, or THC. The Cannabis plant preparation also contains other compounds that are chemically related to THC, called cannabinoids. THC is chemically similar to a class of substances found naturally in our nervous system called endogenous cannabinoids, or endocannabinoids, of which anandamide is best known so far. The endocannabinoids are part of a newly discovered system named the Endocannabinoid system, or ECS. How the ECS works The ECS acts as a modulator of neurotransmission. When the postsynaptic neuron is activated, endocannabinoids are produced, released, and travel back to the presynaptic neuron where they activate cannabinoid receptors. By doing so, they control what happens next when the presynaptic cell is again stimulated. The general effect is a decrease in the release of neurotransmitters such as GABA or glutamate. In other words, the ECS acts as a “brake”, slowing down neuronal activities, preventing neurons from excessive firing. Some examples of ECS functions include: - Pain modulation: cannabinoids suppress pain signal processing, producing pain relief effects. - Stress and anxiety reduction: The ECS has been implicated in the habituation the body’s response to repeated exposure to restraint stress. - Mood regulation: the ECS promotes “good feeling” by inducing dopamine release in the brain reward pathway. This explains the euphoria, or the “high”, experienced by marijuana users. THC mode of action is however different from other drugs: it induces dopamine release INDIRECTLY by removing inhibitory action of GABA on dopaminergic neurons. The ECS is also involved in many more bodily activities, including appetite, memory, learning, sleeping patterns, immune functions and fertility. So how can marijuana be harmful if it does exactly what our body already does to itself? The endocannabinoids are short-acting transmitter substances. They are synthesized on demand and their signaling is rapidly terminated by specific enzymes. Marijuana users consume a much higher amount of THC. THC is also much more stable and can persist in the body for a longer period of time. THC overwhelms the EC system, overriding normal brain functions. Because cannabinoid receptors are present in many parts of the brain and body, the effects of THC are wide-ranging. It can slow down a person’s reaction time, which could impair driving or athletic skills; disrupt short-term memory and higher thought processes, which could affect learning capabilities and judgment ability. Higher doses of THC may also lead to reverse effects. Consuming marijuana by smoking may also damage the lungs to a similar extent as smoking cigarettes. Long - term effects of THC Substantial evidence from animal research indicates that marijuana exposure can cause long-term adverse changes in the brain. Long-term effects of marijuana in human are still debatable mostly due to difficulties of conducting research in human beings. Medical uses of marijuana While recreational use of marijuana is without doubt harmful, the Cannabis plant may be a valuable source of medicines. Currently, the two main cannabinoids from the marijuana plant that are of medical interest are THC and cannabidiol, or CBD. These chemicals are used to increase appetite and reduce nausea in patients undergoing cancer chemotherapy. They may also be useful in reducing pain and inflammation, controlling epileptic seizures, and possibly even treating autoimmune diseases and cancers.
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The CBD is one of the famous cannabinoids found in cannabis. CBD products are becoming increasingly popular due to their endless effects and benefits. There are many products with CBD, such as CBD hemp oil, famous CBD hemp tea, CBD capsules, CBD hemp creams and so on. All these products are known to all, but there are many others. CBD is used to treat conditions such as anxiety, mobility, pain, and heart disease. Products such as cannabis stains and CBD oils have become increasingly popular in recent years and are often recommended by doctors.
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I decided to make a video about some supposed Jennifer Hudson keto gummies (example: Trim Life Keto + ACV Gummies), CBD gummies, or weight loss diet pills, which is all a scam. Hudson has nothing to do with any of this. Scammers were using her image and likeness and the keto gummies company's name without permission. Jennifer Hudson never, ever, endorsed apple cider vinegar (ACV) keto gummies, CBD gummies, diet pills or weight loss supplements, or Trim Life Keto + ACV Gummies. This weight loss scam claimed that Jennifer Hudson endorsed various keto gummies (example: Trim Life Keto + ACV Gummies), CBD gummies, or diet pills products, which was false. This was all a big fake celebrity endorsement scam. She and other celebrities who appear in these scams have nothing to do with these keto or CBD gummies products. Stay far away from all of this nonsense. Let’s make one thing clear. Ree Drummond aka “The Pioneer Woman” and Oprah Winfrey never endorsed any keto or CBD gummies products of any kind, ever. These celebrities have nothing to do with these products. On Facebook, I’ve found no shortage of scam pages that claimed celebrities like Jennifer Hudson endorsed CBD and keto gummies or diet pills or supplements, and many of these pages were recently created. None of this was legitimate. Most of the pages had zero followers, which was obviously a big red flag that something was off. The pages all included links that appeared to perhaps be designed for affiliate marketing. It’s also possible that the scammers had end goals that I wasn’t aware of. If you’ve fallen victim to a CBD or keto gummies scam or fake “review” or bought an Amazon listing that was scammy, please let me know in the comments below. Also, feel free to ask me questions about this scam or any scam. My comments are open. Thank you for watching and feel free to hit “Like” (thumbs up) so that Google knows my video is trustworthy, and so other people, including potential victims of scams, might see what I’ve laid out here. Image Credit: Wikimedia Commons
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本編 https://youtu.be/ZbkA7GySfng CBDの主要な医療用途は、痛み、不安、不眠、うつであることが複数の調査の結果、明らかになっています。今回は2019年にコロラド大学精神科のスコット・シャノン医師が行った、不眠と不安の症状を抱えるCBDの使用者に対してアンケート調査(後ろ向き研究)を紹介します。 ◆Green Zone Japanウェブサイト https://www.greenzonejapan.com 大麻についての正しい知識を日本にも。 趣旨に賛同頂ける方から寄附を受け付けております。 https://syncable.biz/associate/greenzonejapan/ 正高佑志:1985年生まれ。医師。熊本大学医学部卒。医療大麻についての科学情報を発信する一般社団法人Green Zone Japanの代表理事。 書籍:お医者さんがする大麻とCBDの話 https://t.co/JlzM7FuhjB 医療目的にCBD・CBGなどのカンナビノイド製品を使用したい方を対象にカンナビノイド医療患者会(PCAT)を運営しています。 https://www.pcat-japan.com/ #不眠 #不安 #CBD #睡眠障害 #不安障害 #エンドカンナビノイドシステム #カンナビノイド #医療用大麻 #医療大麻
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Hear CEO of Releaf and CEO of Glass Pharms discuss Glass Pharms' extraction methods Let’s rethink healTHCare #medicalcannabis #cannabis #ceo #ceopodcast #thc #cannabisfarm #cannabiseducation #cannabisdaily #cannabisuk #medicine #alternativehealth #cbd #medicine #letsrethinkhealthcare